Evidence map›Paper›PMID 30817215›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Salivary gland immunization

Guangliang Liu, Fangfang Zhang, Ruixue Wang, Steven D London, Lucille London

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Functional drug-delivery hydrogels for oral and maxillofacial wound healing.Frontiers in bioengineering and biotechnology · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Guangliang LiuDepartment of Oral Biology and Pathology, School of Dental Medicine, Stony Brook University, Stony Brook, New York, USA.
Fangfang ZhangDepartment of Oral Biology and Pathology, School of Dental Medicine, Stony Brook University, Stony Brook, New York, USA.
Ruixue WangDepartment of Oral Biology and Pathology, School of Dental Medicine, Stony Brook University, Stony Brook, New York, USA.
Steven D LondonDepartment of Oral Biology and Pathology, School of Dental Medicine, Stony Brook University, Stony Brook, New York, USA.
Lucille LondonDepartment of Oral Biology and Pathology, School of Dental Medicine, Stony Brook University, Stony Brook, New York, USA.
Stony Brook University · USStony Brook School · US

Funding

Oral Immunobiology of MCMV-infected Mouse Salivary GlandsR01DE016652 · NIDCR · STATE UNIVERSITY NEW YORK STONY BROOK · PI LONDON, STEVEN D · 2006 to 2010
$1.7M
Opportunities for Dental Research in Salivary Gland Immunobiology at Stony BrookR15DE024313 · NIDCR · STATE UNIVERSITY NEW YORK STONY BROOK · PI LONDON, STEVEN D · 2015 to 2019
$892k
NIDCR NIH HHS R01 DE016652NIDCR NIH HHS R15 DE024313
6 · The paper itself

Abstract

Salivary glands are a major component of the mucosal immune system that confer adaptive immunity to mucosal pathogens. As previously demonstrated, immunization of the submandibular gland with tissue culture-derived murine cytomegalovirus (tcMCMV) or replication-deficient adenoviruses expressing individual murine cytomegalovirus (MCMV) genes protected mice against a lethal MCMV challenge. Here, we report that salivary gland inoculation of BALB/cByJ mice with tcMCMV or recombinant adenoviruses differentially activates T helper (T

Indexed as

Immunity, MucosalAdenoviridaeAnimalsCytokinesFemaleGATA3 Transcription FactorInterferon-gammaLymph NodesLymphocytesMiceMice, Inbred BALB CMuromegalovirusSalivary DuctsSalivary GlandsT-bet Transcription FactorT-Box Domain ProteinsCytokinesGata3 protein, mouseGATA3 Transcription FactorInterferon-gammaT-bet Transcription FactorT-Box Domain Proteinsmucosal immunityT helper cellsvaccine development

Identifiers

PMID30817215
PMCPMC6463922
OpenAlexW2916347064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.