Evidence map›Paper›PMID 30817183›Full record

ArticleJournal of child and adolescent psychopharmacology2019

CYP2C19-Guided Escitalopram and Sertraline Dosing in Pediatric Patients: A Pharmacokinetic Modeling Study.

Jeffrey R Strawn, Ethan A Poweleit, Laura B Ramsey

Open access · greenAbstract read
In one paragraph

Article in Journal of child and adolescent psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  7. Genetic variants ofJournal of Taibah University Medical Sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jeffrey R Strawn1 Department of Psychiatry and Behavioral Neuroscience, College of Medicine, University of Cincinnati, Cincinnati, Ohio.
Ethan A Poweleit3 Divisions of Research in Patient Services and Clinical Pharmacology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Laura B Ramsey3 Divisions of Research in Patient Services and Clinical Pharmacology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati Medical Center · US

Funding

Estracellular Vesicles as Non-Invasive Predictors of Antidepressant Outcomes in Pediatric AnxietyR01HD098757 · NICHD · UNIVERSITY OF CINCINNATI · PI STRAWN, JEFFREY ROBERT · 2019 to 2024
$2.4M
Neurofunctional Predictors of Treatment Response in Adolescents with GADK23MH106037 · NIMH · UNIVERSITY OF CINCINNATI · PI STRAWN, JEFFREY ROBERT · 2014 to 2017
$745k
NICHD NIH HHS R01 HD098757NIMH NIH HHS K23 MH106037
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAnxiety DisordersCitalopramCytochrome P-450 CYP2C19FemaleHumansMajor Depressive DisorderMalePharmacogenomic TestingPhenotypePolymorphism, GeneticSelective Serotonin Reuptake InhibitorsSertralineCitalopramCYP2C19 protein, humanCytochrome P-450 CYP2C19Selective Serotonin Reuptake InhibitorsSertralinedepressionescitaloprammajor depressive disordersertraline

Identifiers

PMID30817183
PMCPMC6585169
OpenAlexW2919064206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.