ArticleThe Journal of infectious diseases2019
Etiology of Diarrhea Among Hospitalized Children in Blantyre, Malawi, Following Rotavirus Vaccine Introduction: A Case-Control Study.
Article in The Journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Burden ofBMJ global health · 2026Pooled it
- Human adenoviruses in children with gastroenteritis: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Efficacy of ETVAX, a vaccine against enterotoxigenic Escherichia coli-positive diarrhoea in Gambian children: a double-blind, randomised, placebo-controlled, phase 2b trial.The Lancet. Infectious diseases · 2026Trial
- Incidence and aetiology of diarrhoeal disease among children under five years in the post-rotavirus vaccine introduction era in Manhiça District, Mozambique.Tropical medicine and health · 2026Article
- Human astrovirus draft genomes from under-five children presenting with gastroenteritis in Malawi from 2012 to 2024.Microbiology resource announcements · 2026Article
- Article
- Molecular characterization and phylogenetic trends of human adenovirus F in pediatric gastroenteritis cases in Kolkata, West Bengal, India during 2022-2024.Archives of virology · 2026Article
- Risk factors associated with Shigella diarrhea in 6-35-month-olds: A cross-sectional study, Malawi, 2022-2024.PLOS global public health · 2026Article
- Complete genome sequence of aMicrobiology resource announcements · 2025Article
- Report of the draft genome sequences of human sapovirus from children with acute gastroenteritis in Malawi, Southern Africa.Microbiology resource announcements · 2025Article
- Distribution ofPathogens (Basel, Switzerland) · 2025Article
- Draft genome sequences of human adenovirus F associated with acute gastroenteritis in Blantyre, Malawi.Microbiology resource announcements · 2025Article
- Draft genomes of norovirus from stool samples of under-five children presenting with gastroenteritis in Malawi from 2012 to 2024.Microbiology resource announcements · 2025Article
- Shigella and Enterotoxigenic Escherichia coli Have Replaced Rotavirus as Main Causes of Childhood Diarrhea in Rwanda After 10 Years of Rotavirus Vaccination.The Journal of infectious diseases · 2024Article
- Risk Factors forPathogens (Basel, Switzerland) · 2024Article
- Etiology of diarrheal hospitalizations following rotavirus vaccine implementation and association of enteric pathogens with malnutrition among under-five children in India.Gut pathogens · 2024Article
- Semi-quantitative assessment of gastrointestinal viruses in stool samples with Seegene Allplex gastrointestinal panel assays: a solution to the interpretation problem of multiple pathogen detection?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- Article
- The Enterics for Global Health (EFGH)Open forum infectious diseases · 2024Article
- Prevalence of Cryptosporidium and Giardia infections in under-five children with diarrhoea in Blantyre, Malawi.BMC infectious diseases · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Despite rotavirus vaccination, diarrhea remains a leading cause of child mortality. We collected stool specimens from 684 children <5 years of age hospitalized with diarrhea (cases) and 527 asymptomatic community controls for 4 years after rotavirus vaccine introduction in Malawi. Specimens were tested for 29 pathogens, using polymerase chain reaction analysis. Three or more pathogens were detected in 71% of cases and 48% of controls. Pathogens significantly associated with diarrhea included rotavirus (in 34.7% of cases and 1.5% of controls), enteric adenovirus (in 29.1% and 2.7%, respectively), Cryptosporidium (in 27.8% and 8.2%, respectively), heat-stable enterotoxin-producing Escherichia coli (in 21.2% and 8.5%, respectively), typical enteropathogenic E. coli (in 18.0% and 8.3%, respectively), and Shigella/enteroinvasive E. coli (in 15.8% and 5.7%, respectively). Additional interventions are required to prevent diarrhea due to rotavirus and other common causal pathogens.
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