Evidence map›Paper›PMID 30816366›Full record

ArticleEuropean journal of breast health2019

Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study.

Julia de Mello Ramirez Medina, Ingrid de Araujo Trugilho, Giovanna Nunes Belo Mendes, Josiel Guedes Silva, Maria Alexsandra da Silva Paiva, Suzana Sales de Aguiar, Luiz Claudio Santos Thuler, Anke Bergmann

Abstract read
In one paragraph

Article in European journal of breast health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Machine learning-based random forest for predicting decreased quality of life in thyroid cancer patients after thyroidectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia de Mello Ramirez MedinaDepartment of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-0879-0409
Ingrid de Araujo TrugilhoDepartment of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-0672-1824
Giovanna Nunes Belo MendesCEUMA University, Maranhão, Brazil.ORCID https://orcid.org/0000-0002-4520-4168
Josiel Guedes SilvaFederal University of Maranhão, Maranhão, Brazil.ORCID https://orcid.org/0000-0002-1205-188X
Maria Alexsandra da Silva PaivaEstácio College of Amazonas, Manaus, Brazil.ORCID https://orcid.org/0000-0003-2977-1469
Suzana Sales de AguiarDepartment of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-1963-1294
Luiz Claudio Santos ThulerDepartment of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-2550-6537
Anke BergmannDepartment of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-1972-8777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the clinical stage in women diagnosed with breast cancer and the association between clinical stage and Health-related quality of life (HRQoL). MATERIALS AND

methodsThis was a cross-sectional study involving women diagnosed with breast cancer. HRQoL was assessed with European Organization for Research and Treatment of Cancer 30-Item Quality of Life Questionnaire and the Quality of Life Questionnaire Breast Cancer 23. The principal exposure was clinical stage (<IIB versus ≥IIB). Simple linear regression was performed and variables with p<0.20 were selected for the multiple linear regression. The final model was composed of statistically significant variables (p<0.05).

resultsIn total, 302 women were included. The majority (58.9%) had been diagnosed with advanced stage cancer (≥IIB). Those at an advanced clinical stage had poorer role functioning (p=0.029), pain (p<0.001), and symptoms in the breast (p<0.001).

conclusionAdvanced clinical stage at diagnosis was found to be associated with worse health-related quality of life in breast cancer patients.

Indexed as

Breast neoplasmneoplasm stagingquality of life

Identifiers

PMID30816366
PMCPMC6385723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.