Evidence map›Paper›PMID 30816311›Full record

ArticleScientific reports2019

Adiponectin is associated with cardio-metabolic traits in Mexican children.

Juehua He, Carolina Stryjecki, Hudson Reddon, Jesus Peralta-Romero, Roberto Karam-Araujo, Fernando Suarez, Jaime Gomez-Zamudio, Ana Burguete-Garcia, Akram Alyass, Miguel Cruz and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Juehua HeDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Carolina StryjeckiDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Hudson ReddonDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Jesus Peralta-RomeroMedical Research Unit in Biochemistry, Hospital de Especialidades, Centro Médico Nacional Siglo XXI del Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Roberto Karam-AraujoHealth Promotion Division, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Fernando SuarezMedical Research Unit in Biochemistry, Hospital de Especialidades, Centro Médico Nacional Siglo XXI del Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Jaime Gomez-ZamudioMedical Research Unit in Biochemistry, Hospital de Especialidades, Centro Médico Nacional Siglo XXI del Instituto Mexicano del Seguro Social, Mexico City, Mexico.ORCID 0000-0002-4903-2420
Ana Burguete-GarciaCentro de investigación sobre enfermedades infecciosas. Instituto Nacional de Salud Pública. Cuernavaca, Morelos, Mexico.
Akram AlyassDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Miguel CruzMedical Research Unit in Biochemistry, Hospital de Especialidades, Centro Médico Nacional Siglo XXI del Instituto Mexicano del Seguro Social, Mexico City, Mexico. mcruzl@yahoo.com.
David MeyreDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada. meyred@mcmaster.ca.
Mexican Social Security Institute · MXImpact · CAInstituto Nacional de Salud Pública · MXMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adipocyte-derived adiponectin hormone bridges obesity and its cardio-metabolic complications. Genetic variants at the ADIPOQ locus, in ADIPOR1, and ADIPOR2 have been associated with adiponectin concentrations and cardio-metabolic complications in diverse ethnicities. However, no studies have examined these associations in Mexican children. We recruited 1 457 Mexican children from Mexico City. Six genetic variants in or near ADIPOQ (rs182052, rs2241766, rs266729, rs822393), ADIPOR1 (rs10920533), and ADIPOR2 (rs11061971) were genotyped. Associations between serum adiponectin, genetic variants, and cardio-metabolic traits were assessed using linear and logistic regressions adjusted for age, sex, and recruitment center. Serum adiponectin concentration was negatively associated with body mass index, waist to hip ratio, low-density lipoprotein cholesterol, total cholesterol, triglycerides, fasting glucose, fasting insulin, homeostatic model assessment of insulin resistance, dyslipidemia and overweight/obesity status (7.76 × 10

Indexed as

AdiponectinAdolescentBlood GlucoseBlood PressureBody Mass IndexChildChild, PreschoolCholesterol, LDLDyslipidemiasFemaleGlucoseHumansInsulinInsulin ResistanceMaleMetabolic DiseasesAdiponectinADIPOQ protein, humanADIPOR1 protein, humanADIPOR2 protein, humanBlood GlucoseCholesterol, LDLGlucoseInsulinReceptors, AdiponectinTriglycerides

Identifiers

PMID30816311
PMCPMC6395686
OpenAlexW2916800975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.