ArticleScientific reports2019
Distinct online and offline effects of alpha and beta transcranial alternating current stimulation (tACS) on continuous bimanual performance and task-set switching.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- No aftereffects of high current density 10 Hz and 20 Hz tACS on sensorimotor alpha and beta oscillations.Scientific reports · 2021Trial
- Individual differences in neuroanatomy and neurophysiology predict effects of transcranial alternating current stimulation.Brain stimulationTrial
- Behaviourally driven closed-loop beta-tACS enhances beta activity and motor behaviour.Nature communications · 2026Article
- Driving motor cortex oscillations restores plasticity and improves bradykinesia features in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Variable E-field properties of dual-site tACS with phase lags.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- The Modulatory Effects of Transcranial Alternating Current Stimulation on Brain Oscillatory Patterns in the Beta Band in Healthy Older Adults.Brain sciences · 2024Article
- Carry-Over Effect of Deep Cerebellar Stimulation-Mediated Motor Recovery in a Rodent Model of Traumatic Brain Injury.Neurorehabilitation and neural repair · 2024Article
- The effect of transcranial alternating current stimulation on cognitive flexibility and attention of children with intellectual disability: a case report.Journal of medical case reports · 2024Article
- Beta tACS of varying intensities differentially affect resting-state and movement-related M1-M1 connectivity.Frontiers in neuroscience · 2024Article
- Neuromodulatory effects of transcranial electrical stimulation on emotion regulation in internalizing psychopathologies.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Article
- Beta rhythmicity in human motor cortex reflects neural population coupling that modulates subsequent finger coordination stability.Communications biology · 2022Article
- Addressing transcranial electrical stimulation variability through prospective individualized dosing of electric field strength in 300 participants across two samples: the 2-SPED approach.Journal of neural engineering · 2022Article
- Article
- The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age.Communications biology · 2022Article
- Behavioral and electrocortical effects of transcranial alternating current stimulation during advice-guided decision-making.Neuroimage. Reports · 2021Article
- Motor Learning Based on Oscillatory Brain Activity Using Transcranial Alternating Current Stimulation: A Review.Brain sciences · 2021Review
- Behavioral Induction of a High Beta State in Sensorimotor Cortex Leads to Movement Slowing.Journal of cognitive neuroscience · 2021Article
- Transcranial Alternating Current Stimulation (tACS) Does Not Affect Sports People's Explosive Power: A Pilot Study.Frontiers in human neuroscience · 2021Article
- Investigating Different Levels of Bimanual Interaction With a Novel Motor Learning Task: A Behavioural and Transcranial Alternating Current Stimulation Study.Frontiers in human neuroscience · 2021Article
- Transient Amplitude Modulation of Alpha-Band Oscillations by Short-Time Intermittent Closed-Loop tACS.Frontiers in human neuroscience · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study we examined the effect of bihemispheric in-phase synchronization of motor cortical rhythms on complex bimanual coordination. Twenty young healthy volunteers received 10 Hz or 20 Hz tACS in a double-blind crossover design while performing a bimanual task-set switching paradigm. We used a bilateral high-density montage centred over the hand knob representation within the primary motor cortices to apply tACS time-locked to the switching events. Online tACS in either frequency led to faster but more erroneous switching transitions compared to trials without active stimulation. When comparing stimulation frequencies, 10 Hz stimulation resulted in higher error rates and slower switching transitions than 20 Hz stimulation. Furthermore, the stimulation frequencies showed distinct carry-over effects in trials following stimulation trains. Non-stimulated switching transitions were generally faster but continuous performance became more erroneous over time in the 20 Hz condition. We suggest that the behavioural effects of bifocal in-phase tACS are explained by online synchronization of long-range interhemispheric sensorimotor oscillations, which impacts on interhemispheric information flow and the top-down control required for flexible control of complex bimanual actions. Different stimulation frequencies may lead to distinct offline effects, which potentially accumulate over time and therefore need to be taken into account when evaluating subsequent performance.
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