Evidence map›Paper›PMID 30816203›Full record

ArticleScientific reports2019

The kidney anion exchanger 1 affects tight junction properties via claudin-4.

Rawad Lashhab, Alina C Rumley, Denis Arutyunov, Midhat Rizvi, Charlotte You, Henrik Dimke, Nicolas Touret, Richard Zimmermann, Martin Jung, Xing-Zhen Chen and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. eLife · 2026
    Article
  2. Article
  3. Article
  4. The role of claudins in homeostasis.Nature reviews. Nephrology · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Rawad LashhabDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Alina C RumleyDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Denis ArutyunovDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Midhat RizviDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Charlotte YouDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Henrik DimkeCardiovascular and Renal research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-9170-2168
Nicolas TouretDepartment of Biochemistry and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Richard ZimmermannDepartment School of Medicine, Medical Biochemistry and Molecular Biology, Saarland University, Homburg, Germany.
Martin JungDepartment School of Medicine, Medical Biochemistry and Molecular Biology, Saarland University, Homburg, Germany.ORCID 0000-0002-1482-7020
Xing-Zhen ChenDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Todd AlexanderDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada.
Emmanuelle CordatDepartment of Physiology and Membrane Protein Disease Research Group, University of Alberta, Edmonton, Alberta, Canada. cordat@ualberta.ca.ORCID 0000-0001-9875-5804
University of Alberta · CASaarland University · DEUniversity of Southern Denmark · DK

Funding

CIHR MOP 136891CIHR MOP 142251
6 · The paper itself

Abstract

In the renal collecting duct, intercalated cells regulate acid-base balance by effluxing protons through the v-H

Indexed as

AnimalsAnion Exchange Protein 1, ErythrocyteBiological TransportCell LineCell Membrane PermeabilityChloridesClaudin-4Electric ImpedanceKidneyKidney Tubules, CollectingMiceSodiumTight JunctionsAnion Exchange Protein 1, ErythrocyteChloridesClaudin-4Cldn4 protein, mouseSLC4A1 protein, humanSodium

Identifiers

PMID30816203
PMCPMC6395713
OpenAlexW2919579517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.