Evidence map›Paper›PMID 30816171›Full record

ArticleScientific reports2019

Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure.

Simei Sun, Hae Jin Kee, Yuhee Ryu, Sin Young Choi, Gwi Ran Kim, Hyung-Seok Kim, Seung-Jung Kee, Myung Ho Jeong

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Therapeutic Potential of Plant Phenolic Acids Combating Cancer Drug Resistance.Recent advances in food, nutrition & agriculture · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Simei SunZhoushan Hospital, Zhejiang University School of Medicine, No 739, Dingshen Road Lincheng New District, Zhoushan Zhejiang, 316021, China.
Hae Jin KeeHeart Research Center of Chonnam National University Hospital, Gwangju, 61469, Republic of Korea. sshjkee@empas.com.
Yuhee RyuHeart Research Center of Chonnam National University Hospital, Gwangju, 61469, Republic of Korea.
Sin Young ChoiHeart Research Center of Chonnam National University Hospital, Gwangju, 61469, Republic of Korea.
Gwi Ran KimHeart Research Center of Chonnam National University Hospital, Gwangju, 61469, Republic of Korea.
Hyung-Seok KimDepartment of Forensic Medicine, Chonnam National University Medical School, Gwangju, 61469, Republic of Korea.
Seung-Jung KeeDepartment of Laboratory Medicine, Chonnam National University, Medical School and Hospital, Gwangju, 61469, Republic of Korea.
Myung Ho JeongHeart Research Center of Chonnam National University Hospital, Gwangju, 61469, Republic of Korea. myungho@chollian.net.
Chonnam National University Hospital · KRChonnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that gentisic acid attenuates cardiac hypertrophy and fibrosis in transverse aortic constriction (TAC)-induced cardiac hypertrophy. Here, we examined whether gentisic acid prevents the development of heart failure. Heart failure was induced in mice via chronic TAC. Mice were administered the vehicle, gentisic acid (10 and 100 mg∙kg

Indexed as

AnimalsCardiomegalyDisease Models, AnimalFibrosisGentisatesHeart FailureMaleMiceMyocardiumMyocytes, Cardiac2,5-dihydroxybenzoic acidGentisates

Identifiers

PMID30816171
PMCPMC6395621
OpenAlexW2915698801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.