Evidence map›Paper›PMID 30816068›Full record

ArticleStem cells and development2019

Dentinogenesis and Tooth-Alveolar Bone Complex Defects in

Xia Huang, Feilong Wang, Chen Zhao, Sheng Yang, Qianyu Cheng, Yingying Tang, Fugui Zhang, Yan Zhang, Wenping Luo, Chao Wang and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Stem cells and development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  5. Genes & diseases · 2026
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  7. Review
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  12. The effect of BMP9 on inflammation in the early stage of pulpitis.Journal of applied oral science : revista FOB · 2023
    Article
  13. Review
  14. Article
  15. Review
  16. Therapeutic effects of peptide P140 in a mouse periodontitis model.Cellular and molecular life sciences : CMLS · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Xia Huang1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Feilong Wang2 Department of Pediatric Dentistry, The Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing, China.
Chen Zhao4 Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Sheng Yang1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Qianyu Cheng1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Yingying Tang1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Fugui Zhang1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Yan Zhang1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Wenping Luo1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Chao Wang1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Pengfei Zhou1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Stephanie Kim6 Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois.
Guowei Zuo7 Ministry of Education Key Laboratory of Diagnostic Medicine and School of Laboratory Medicine, Chongqing Medical University, Chongqing, China.
Ning Hu4 Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ruidong Li8 Department of Orthopaedic Surgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Tong-Chuan He1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Hongmei Zhang1 Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China.
Stomatological Hospital of Chongqing Medical University · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CNUniversity of Chicago Medical Center · USChildren's Hospital of Chongqing Medical University · CNDalian Medical University · CN

Funding

A genomewide discovery of chemoresistance-associated noncoding RNAs in human cancersR21CA226303 · NCI · UNIVERSITY OF CHICAGO · PI HE, TONG-CHUAN · 2018 to 2019
$381k
NCI NIH HHS R21 CA226303
6 · The paper itself

Abstract

Tooth development is regulated by sequential and reciprocal epithelium-mesenchymal interactions and their related molecular signaling pathways, such as bone morphogenetic proteins (BMPs). Among the 14 types of BMPs, BMP9 (also known as growth differentiation factor 2) is one of the most potent BMPs to induce osteogenic differentiation of mesenchymal stem cells. The purpose of this study was to examine potential roles of BMP9 signaling in tooth development. First, we detected the expression pattern of BMP9 in tooth germ during postnatal tooth development, and we found that BMP9 was widely expressed in odontoblasts, ameloblasts, dental pulp cells, and osteoblasts in alveolar bones. Then, we established a

Indexed as

AmeloblastsAnimalsCell DifferentiationDental PulpDentinDentinogenesis ImperfectaDentin SialophosphoproteinEpithelial-Mesenchymal TransitionExtracellular Matrix ProteinsGene Expression RegulationGrowth Differentiation Factor 2Mesenchymal Stem CellsMiceMice, Inbred C57BLMice, KnockoutOdontoblastsDentin SialophosphoproteinDmp1 protein, mouseExtracellular Matrix ProteinsGdf2 protein, mouseGrowth Differentiation Factor 2PhosphoproteinsSialoglycoproteinsbone morphogenetic protein 9dental stem cellsdentinogenesisdentinogenesis imperfectaodontoblastic differentiationtooth development

Identifiers

PMID30816068
PMCPMC6534167
OpenAlexW2918216212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.