Evidence map›Paper›PMID 30816054›Full record

ArticlePersonalized medicine2019

Clinical and research applications of a brain tumor tissue bank in the age of precision medicine.

James Snyder, Laila M Poisson, Houtan Noushmehr, Ana V Castro, Ana C deCarvalho, Adam Robin, Abir Mukherjee, Ian Lee, Tobias Walbert

Abstract readEditorial
In one paragraph

Article in Personalized medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

James SnyderDepartment of Neurology, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Laila M PoissonDepartment of Neurosurgery, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Houtan NoushmehrDepartment of Neurosurgery, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Ana V CastroDepartment of Neurosurgery, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Ana C deCarvalhoDepartment of Neurosurgery, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Adam RobinDepartment of Neurosurgery, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Abir MukherjeeDepartment of Pathology, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Ian LeeDepartment of Neurosurgery, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.
Tobias WalbertDepartment of Neurology, 2799 W Grand Blvd, Henry Ford Health System, Detroit, MI 48202 USA.

Funding

Molecular and clinical evaluation of the glioma patient experience to anticipate modern outcomes and guide patient careR01CA222146 · NCI · HENRY FORD HEALTH SYSTEM · PI POISSON, LAILA M · 2018 to 2023
$2.8M
NCI NIH HHS R01 CA222146
6 · The paper itself

Abstract

Marked progress has been made recently in the treatment of patients with central nervous system (CNS) tumors, especially gliomas. However, because of the relative rarity of these tumors compared with other malignancies, advances in the molecular/genetic analysis leading to future targeted treatments rely on systematic, organized tissue banking. Several large multi-institutional efforts have utilized major tissue banks that have yielded valuable information that may lead to a better understanding of the pathogenesis of CNS tumors. This manuscript portrays best practices for the establishment and maintenance of a well-organized CNS tumor bank. In addition, annotation for clinical and research needs is explained. The potential benefits to clinical care, as well as basic science and translational research are also described.

Indexed as

BrainBrain NeoplasmsCentral Nervous System NeoplasmsGliomaHumansPrecision MedicineTissue BanksTranslational Research, Biomedical

Identifiers

PMID30816054
PMCPMC6598053

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.