ArticleJournal of cachexia, sarcopenia and muscle2019
Exercise with blood flow restriction: an effective alternative for the non-pharmaceutical treatment for muscle wasting.
Article in Journal of cachexia, sarcopenia and muscle, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- A call to action for blood flow restriction training in older adults with or susceptible to sarcopenia: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Effects of blood flow restriction training on anthropometric and blood lipids in overweight/obese adults: Meta-analysis.Frontiers in physiology · 2022Pooled it
- Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Trial
- Acute and chronic cardiometabolic responses induced by resistance training with blood flow restriction in HIV patients.Scientific reports · 2022Trial
- Partial ischemia as molecular medicine: molecular mechanisms and clinical horizons of blood flow restriction training.Frontiers in physiology · 2026Review
- Mechanistic interactions of diet, exercise, and pharmacotherapy in skeletal muscle metabolism: evidence and translational perspectives.Frontiers in physiology · 2026Review
- Examining the impact of blood flow restriction on cardiac rehabilitation outcomes.World journal of cardiology · 2025Review
- Blood flow restriction training in microgravity: a review of multisystem physiological benefits and implementation challenges for long-duration space missions.NPJ microgravity · 2025Review
- Blood flow restriction training: a new approach for preventing and treating sarcopenia in older adults.Frontiers in physiology · 2025Review
- Disuse-Induced Muscle Fatigue: Facts and Assumptions.International journal of molecular sciences · 2024Review
- Physiological and perceptual responses to acute arm cranking with blood flow restriction.European journal of applied physiology · 2024Article
- Feasibility of Blood Flow Restriction Exercise in Adults with a Non-surgically Treated Achilles Tendon Rupture; a Case Series.International journal of exercise science · 2024Article
- Engineered muscle from micro-channeled PEG scaffold with magnetic FeMaterials today. Bio · 2023Article
- Effects of blood-flow restricted exercise versus conventional resistance training in musculoskeletal disorders-a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2023Article
- Blood Flow Restriction in Oncological Patients: Advantages and Safety Considerations.Healthcare (Basel, Switzerland) · 2023Review
- Low-load exercises with concurrent blood flow restriction as rehabilitation for unspecific knee pain to a former American football player: A case report.SAGE open medical case reports · 2023Article
- Patterns of vascular response immediately after passive mobilization in patients with sepsis: an observational transversal study.The international journal of cardiovascular imaging · 2022Observational
- Blood Flow Restriction Training for the Intervention of Sarcopenia: Current Stage and Future Perspective.Frontiers in medicine · 2022Review
- Invasive Assessment of Hemodynamic, Metabolic and Ionic Consequences During Blood Flow Restriction Training.Frontiers in physiology · 2020Article
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significant muscle wasting is generally experienced by ill and bed rest patients and older people. Muscle wasting leads to significant decrements in muscle strength, cardiorespiratory, and functional capacity, which increase mortality rates. As a consequence, different interventions have been tested to minimize muscle wasting. In this regard, blood flow restriction (BFR) has been used as a novel therapeutic approach to mitigate the burden associated with muscle waste conditions. Evidence has shown that BFR per se can counteract muscle wasting during immobilization or bed rest. Moreover, BFR has also been applied while performing low intensity resistance and endurance exercises and produced increases in muscle strength and mass. Endurance training with BFR has also been proved to increase cardiorespiratory fitness. Thus, frail patients can benefit from exercising with BFR due to the lower cardiovascular and join stress compared with traditional high intensity exercises. Therefore, low intensity resistance and endurance training combined with BFR may be considered as a novel and attractive intervention to counteract muscle wasting and to decrease the burden associated with this condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.