ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021
FDG-PET in possible cardiac sarcoidosis: Right ventricular uptake and high total cardiac metabolic activity predict cardiovascular events.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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24 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The prognostic role of cardiac positron emission tomography imaging in patients with sarcoidosis: A systematic review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Pooled it
- Revisiting Perfusion in the Forgotten Right Ventricle: Artificial Intelligence-Enhanced Quantification on PET/CT.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026Article
- Strict carbohydrate restriction enables volume-based FDG-PET/CT to outperform SUVmax for risk stratification in cardiac sarcoidosis.International journal of cardiology. Heart & vasculature · 2026Article
- Tofacitinib in the treatment of cardiac sarcoidosis: towards steroid-sparing disease management.Open heart · 2026Article
- Beyond the Biopsy: Imaging Frontiers in Cardiac Sarcoidosis.Cardiology research and practice · 2026Review
- The Role of Imaging in Ventricular Tachycardia Ablation.Diagnostics (Basel, Switzerland) · 2025Review
- Myocardial-to-background ratio in F18-fluorodeoxyglucose PET in cardiac sarcoidosis for diagnosis and evaluation of therapeutic response.International journal of cardiology. Heart & vasculature · 2025Article
- AI-enabled CT-guided end-to-end quantification of total cardiac activity in 18FDG cardiac PET/CT for detection of cardiac sarcoidosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025Article
- Prognostic value of multimodality imaging in the contemporary management of cardiac sarcoidosis.Open heart · 2024Article
- Machine learning approach usingJapanese journal of radiology · 2024Article
- Sarcoid heart disease and imaging.Heart rhythm O2 · 2024Review
- Echocardiography in inflammatory heart disease: A comparison of giant cell myocarditis, cardiac sarcoidosis, and acute non-fulminant myocarditis.International journal of cardiology. Heart & vasculature · 2023Article
- FDG uptake patterns in isolated and systemic cardiac sarcoidosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- QCard-NM: Developing a semiautomatic segmentation method for quantitative analysis of the right ventricle in non-gated myocardial perfusion SPECT imaging.EJNMMI physics · 2023Article
- Assessment of treatment response in cardiac sarcoidosis based on myocardialFrontiers in immunology · 2023Article
- Enhancement ofDiagnostics (Basel, Switzerland) · 2022Article
- Right ventricular longitudinal strain on CMR predicts ventricular arrhythmias and mortality in cardiac sarcoidosis.American heart journal plus : cardiology research and practice · 2022Article
- The role of PET in the management of sarcoidosis.Current opinion in pulmonary medicine · 2022Review
- Potential roles ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
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6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac involvement accounts for the majority of morbidity and mortality in sarcoidosis. Pathological myocardial fluorodeoxyglucose (FDG)-uptake in positron emission tomography (PET) has been associated with cardiovascular events and quantitative metabolic parameters have been shown to add prognostic value. Our aim was to study whether the pattern of pathological cardiac FDG-uptake and quantitative parameters are able to predict cardiovascular events in patients with suspected cardiac sarcoidosis (CS).
methods137 FDG-PET examinations performed in Tampere University Hospital were retrospectively analyzed visually and quantitatively. Location of pathological uptake was noted and pathological metabolic volume, average standardized uptake value (SUV), and total cardiac metabolic activity (tCMA) were calculated. Patients were followed for ventricular tachycardia, decrease in left ventricular ejection fraction, and death.
resultsEleven patients had one or more cardiovascular events during the follow-up. Five patients out of 12 with uptake in both ventricles had an event during follow-up. Eight patients had high tCMA (> 900 MBq) and three of them had a cardiovascular event. Right ventricular uptake and tCMA were significantly associated with cardiovascular events during follow-up (P-value .001 and .018, respectively).
conclusionsHigh tCMA and right ventricular uptake were significant risk markers for cardiac events among patient with suspected CS.
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