Evidence map›Paper›PMID 30815744›Full record

ReviewCurrent cardiology reports2019

Quantification of PET Myocardial Blood Flow.

Matthieu Pelletier-Galarneau, Patrick Martineau, Georges El Fakhri

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Visually assessed ischemia on cardiac magnetic resonance, but not quantitative perfusion metrics, predicts symptomatic improvement in coronary artery bypass.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Non-invasive diagnosis of vasospastic angina.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  10. Development and evaluation of a radiomics model of restingAnnals of translational medicine · 2022
    Article
  11. On the relationship between coronary microvascular disease and obesity.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  12. Review
  13. Let's embrace optical imaging: a growing branch on the clinical molecular imaging tree.European journal of nuclear medicine and molecular imaging · 2021
    Article
  14. A big step towards clinical implementation of myocardial blood flow quantification with CZT SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  15. The potential of regional myocardial blood flow measurement with SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  16. Comparison of myocardial blood flow and flow reserve with dobutamine and dipyridamole stress using rubidium-82 positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  17. Review
  18. Review
  19. Review
  20. The potential for PET-guided revascularization of coronary artery disease.European journal of nuclear medicine and molecular imaging · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthieu Pelletier-GalarneauGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Patrick MartineauGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Georges El FakhriGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. elfakhri@pet.mgh.harvard.edu.

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
NIBIB NIH HHS P41 EB022544
6 · The paper itself

Abstract

purpose of reviewThe aim of this review is to provide an update on quantification of myocardial blood flow (MBF) with positron emission tomography (PET) imaging. Technical and clinical aspects of flow quantification with PET are reviewed. RECENT

findingsThe diagnostic and prognostic values of myocardial flow quantification have been established in numerous studies and in various populations. MBF quantification has also shown itself to be particularly useful in the assessment of coronary microvascular dysfunction and in evaluation of cardiac allograft vasculopathy. Overall, myocardial flow reserve (MFR) and hyperemic MBF can lead to improved risk stratification by providing information complementary to that of other markers of disease severity, such as fractional flow reserve. Flow quantification enhances MPI's ability to detect both significant epicardial disease and microvascular dysfunction. With recent technological and methodological advances, flow quantification with PET is no longer restricted to cyclotron-equipped academic centers.

Indexed as

Fractional Flow Reserve, MyocardialCoronary AngiographyCoronary Artery DiseaseCoronary CirculationHumansMicrocirculationMicrovesselsMyocardial Perfusion ImagingPositron-Emission TomographyCoronary artery diseaseMyocardial blood flowMyocardial flow reserveMyocardial perfusion imagingPositron emission tomography

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.