ArticleEndocrinology, diabetes & metabolism2018
Paediatric Anti-Müllerian Hormone measurement: Male and female reference intervals established using the automated Beckman Coulter Access AMH assay.
Article in Endocrinology, diabetes & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Gonadotropin Therapy for Mini-Puberty Induction in Male Infants With Hypogonadotropic Hypogonadism.The Journal of clinical endocrinology and metabolism · 2025Pooled it
- Clinical Utility of Anti-Mullerian Hormone in Pediatrics.The Journal of clinical endocrinology and metabolism · 2022Pooled it
- Longitudinal Ovarian Reserve in Female Adolescents/Young Adults With Lymphoma: A Report From Children's Oncology Group Study ALTE11C1.Pediatric blood & cancer · 2026Article
- Genetic landscape of a neonatal hypogonadotropic hypogonadism series: Novel variants and phenotypic spectrum.Journal of neuroendocrinology · 2026Article
- Practical considerations for AMH interpretation in female children and adolescents.Hormones (Athens, Greece) · 2026Article
- Gonadal Function and Its Evolution in 46,XX Testicular/Ovotesticular DSD.The Journal of clinical endocrinology and metabolism · 2026Article
- Balancing oncologic risk and fertility potential: a single-center study on Turner syndrome patients with Y chromosome material.Frontiers in endocrinology · 2026Article
- Age- and sex-specific reference intervals for anti-Müllerian hormone during childhood in Chinese population: a cross-sectional study of 2,450 healthy children.Translational pediatrics · 2025Article
- Role of the pediatrician in the initial management of a newborn with Differences of Sex Development or hypospadias.European journal of pediatrics · 2025Review
- Clinical utility of anti-Müllerian hormone in female children and adolescents.Hormones (Athens, Greece) · 2025Review
- Analytical performances of a novel fluorescent immunoassay of anti-Müllerian hormone and establishment of the reference intervals in Chinese children.Practical laboratory medicine · 2024Article
- Mini-Puberty, Physiological and Disordered: Consequences, and Potential for Therapeutic Replacement.Endocrine reviews · 2024Review
- Serum anti-Müllerian hormone is lower in patients with multiple radioiodine dose for treatment of pediatric thyroid cancer.European thyroid journal · 2024Article
- Radioiodine treatment in female survivors of pediatric differentiated thyroid carcinoma does not affect future pregnancy rates.Archives of endocrinology and metabolism · 2024Article
- Is ongoing testosterone required after pubertal induction in Duchenne muscular dystrophy?Endocrine connections · 2023Article
- The Stability of the Anti-Müllerian Hormone in Serum and Plasma Samples under Various Preanalytical Conditions.Diagnostics (Basel, Switzerland) · 2023Article
- The Cut-Off Value of Serum Anti-Müllerian Hormone Levels for the Diagnosis of Turner Syndrome with Spontaneous Puberty.International journal of endocrinology · 2023Article
- Criteria for Diagnosis of Polycystic Ovary Syndrome during Adolescence: Literature Review.Diagnostics (Basel, Switzerland) · 2022Review
- Gonadectomy in Individuals with Turner Syndrome and Y Chromosome Material: Fertility Considerations.Journal of pediatric and adolescent gynecology · 2022Article
- Biallelic variants inJournal of medical genetics · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAnti-Müllerian Hormone (AMH) concentration is high at birth in males, demonstrating the presence of functional testicular tissue in the prepubertal period, and acting as a useful marker in the investigation of paediatric reproductive disorders. AMH also provides a tool in the investigation of female virilization, premature ovarian failure and polycystic ovarian syndrome in childhood. Robust, assay-specific paediatric AMH reference intervals are therefore required for clinical interpretation of results. The aim of this study was to derive age-specific AMH reference intervals for males and females aged 0-18 years. DESIGN AND PATIENTS: Plasma samples were obtained from patients at Royal Manchester Children's Hospital and analysed for AMH using the automated Beckman Coulter Access AMH Assay. Patients under investigation for paediatric reproductive or endocrine disorders were excluded from the study. MEASUREMENTS: Seven hundred and 2 patient plasma samples (465 male, 237 female) were subject to AMH measurement, and results were analysed in order to derive continuous and discrete reference intervals for the paediatric age range.
resultsClear discrimination between male and female AMH results was evident in the prepubertal age range, with some overlap between the genders following pubertal onset.
conclusionsWe have derived age-related reference intervals for plasma AMH in the paediatric age range (0-18 years) using the automated Beckman Coulter Access AMH assay which will aid in the investigation of paediatric endocrine disorders such as disorders of sexual development.
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