Evidence map›Paper›PMID 30815548›Full record

ArticleEndocrinology, diabetes & metabolism2018

Severity of hypoglycaemia and health-related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe.

Manjiri Pawaskar, Edward A Witt, Samuel S Engel, Swapnil N Rajpathak, Kristy Iglay

Abstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Review
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  9. Family Members: The Forgotten Players in the Diabetes Care Team (The TALK-HYPO Study).Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manjiri PawaskarMerck & Co. Inc. Kenilworth NJ USA.ORCID 0000-0001-8009-805X
Edward A WittKantar Health Princeton NJ USA.
Samuel S EngelMerck & Co. Inc. Kenilworth NJ USA.
Swapnil N RajpathakMerck & Co. Inc. Kenilworth NJ USA.
Kristy IglayMerck & Co. Inc. Kenilworth NJ USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsHypoglycaemia in patients with type 2 diabetes mellitus (T2DM) is associated with poor health outcomes, such as reduced health-related quality of life (HRQoL). This study aimed to assess the impact of hypoglycaemic events by severity on HRQoL, work productivity and healthcare costs in patients with T2DM. MATERIALS AND

methodsEuropean patients with T2DM selected from the National Health and Wellness Survey who were currently receiving pharmacologic therapy were stratified into 3 groups based on the reported history and severity of hypoglycaemic events (no event, nonsevere, severe) experienced in the previous 3 months. Patients' work productivity, HRQoL, healthcare resource use (HCRU) and associated costs were assessed as self-reported outcomes.

resultsOf 1269 patients included in the study, 652 (51.4%) patients had not experienced an event, while 533 (42.0%) and 84 (6.6%) patients had experienced nonsevere and severe hypoglycaemic events, respectively, in the previous 3 months. An increase in hypoglycaemia severity was associated with a decrease in HRQoL, and an increase in HCRU and healthcare costs.

conclusionsThe impact of hypoglycaemia varies by severity and has a negative impact on HRQoL and overall HCRU and costs.

Indexed as

economic burdenhealthcare resource usehealth‐related quality of lifehypoglycaemiatype 2 diabetes mellituswork productivity

Identifiers

PMID30815548
PMCPMC6354814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.