Evidence map›Paper›PMID 30815288›Full record

ReviewFood science and biotechnology2019

Soy-derived phytoalexins: mechanism of in vivo biological effectiveness in spite of their low bioavailability.

Jisun Oh, Chan Ho Jang, Jong-Sang Kim

Open access · bronzeAbstract readReview
In one paragraph

Review in Food science and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jisun Oh1School of Food Science and Biotechnology (BK21 PLUS Program), Kyungpook National University, Daegu, 41566 Republic of Korea.
Chan Ho Jang1School of Food Science and Biotechnology (BK21 PLUS Program), Kyungpook National University, Daegu, 41566 Republic of Korea.
Jong-Sang Kim1School of Food Science and Biotechnology (BK21 PLUS Program), Kyungpook National University, Daegu, 41566 Republic of Korea.ORCID 0000-0003-0483-7230
Kyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The well-demonstrated bioefficacy of phytochemicals in spite of their paradoxically low bioavailability has long puzzled scientists. Glyceollins, a family of soy-derived phytoalexins, have been reported to exert a variety of biological effects in vitro and in vivo systems in spite of poor systemic bioavailability after oral administration, suggesting that secondary messengers generated in gastrointestinal tract would transfer signals to target organs and tissues to manifest any effect. This review focuses on the potential mechanisms of how the poorly bioavailable glyceollins could still exert in vivo biological effects.

Indexed as

Carbon monoxideGlyceollinsHeme oxygenasesNrf2Phytochemicals

Identifiers

PMID30815288
PMCPMC6365327
OpenAlexW2898555492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.