Evidence map›Paper›PMID 30815261›Full record

ArticleSAGE open medical case reports2019

Invasive melanoma in a 5-year-old Canadian patient: A case report.

Joanna Yuen, Fatmah AlZahrani, Garnet Horne, Karen Naert, Timothy McCalmont, Kathy Unger, Loretta Fiorillo

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in SAGE open medical case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joanna YuenDivision of Dermatology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Fatmah AlZahraniDivision of Dermatology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Garnet HorneDepartment of Pathology and Laboratory Medicine, Red Deer Regional Hospital, Red Deer, AB, Canada.
Karen NaertDepartment of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada.
Timothy McCalmontDepartment of Pathology and Dermatology, University of California San Francisco, San Francisco, CA, USA.
Kathy UngerFamily Medical Associates, Lacombe, AB, Canada.
Loretta FiorilloDivision of Dermatology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical Spitzoid lesions pose a distinct challenge in classification as they may comprise a mixture of both classic benign nevus and cutaneous melanoma characteristics. Immunostaining and molecular analysis, such as comparative genomic hybridization, can assist in narrowing the differential diagnosis. We present a case of a 5-year-old male with an atypical Spitzoid lesion on his back. Initial histopathology revealed a relatively symmetric lesion with mitotic figures and poor maturation of melanocytes with descent into the dermis. Immunohistochemistry demonstrated a loss of p16, and array comparative genomic hybridization revealed a loss of chromosome 9, supporting a diagnosis of invasive melanoma arising in conjunction with a remnant of a conventional melanocytic nevus. This case is the first in Canada to demonstrate the use of array comparative genomic hybridization for diagnosing melanoma in a young paediatric patient.

Indexed as

atypical Spitz neviimmunostainingMalignant melanomamolecular analysis

Identifiers

PMID30815261
PMCPMC6381421

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.