Evidence map›Paper›PMID 30815205›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2018

Learning When Communications Between Healthcare Providers Indicate Hormonal Therapy Medication Discontinuation.

Zhijun Yin, Jeremy L Warner, Bradley A Malin

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhijun YinVanderbilt University Medical Center, Nashville, Tennessee, USA.
Jeremy L WarnerVanderbilt University Medical Center, Nashville, Tennessee, USA.
Bradley A MalinVanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hormonal therapy is an effective yet challenging long-term treatment for patients with hormone receptor positive breast cancer. Understanding what factors indicate discontinuation of a recommended hormonal therapy medication can help improve treatment experience. To date, studies on medication discontinuation have focused on patient information gathered through questionnaires, structured electronic medical records and online discussion boards. However, there has been little investigation into the communications between healthcare providers, which may provide additional indicators of patients' medication discontinuation, particularly from a clinical perspective. In this paper, we investigate the relation between such communications and hormonal therapy medication discontinuation. We studied a cohort of 2,579 patients on hormonal therapy at the Vanderbilt University Medical Center over a 16-year period. We adopt a data-driven approach to investigate the clinical messages communicated by their healthcare providers, the messaging patterns, topics they communicated, and the extent to which these factors are affiliated with discontinuation to a recommended 5-year treatment protocol. Our findings suggest that notification of unread messages, plans for clinical trials and the occurrence of treatment-related complications are affiliated with an increased risk of medication discontinuation. By contrast, ordering prescriptions, making appointments, using positive communication verbs, and noting patients' stable health conditions are affiliated with a decreased risk of medication discontinuation.

Indexed as

CommunicationHealth PersonnelMedical Records Systems, ComputerizedMedication AdherenceAntineoplastic Agents, HormonalBreast NeoplasmsCohort StudiesElectronic Health RecordsFemaleHumansProportional Hazards ModelsAntineoplastic Agents, Hormonal

Identifiers

PMID30815205
PMCPMC6371302

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.