Evidence map›Paper›PMID 30815053›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2018

A Computable Phenotype for Acute Respiratory Distress Syndrome Using Natural Language Processing and Machine Learning.

Majid Afshar, Cara Joyce, Anthony Oakey, Perry Formanek, Philip Yang, Matthew M Churpek, Richard S Cooper, Susan Zelisko, Ron Price, Dmitriy Dligach

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Advances in Biomarkers for Diagnosis and Treatment of ARDS.Diagnostics (Basel, Switzerland) · 2023
    Review
  10. Review
  11. Article
  12. Machine learning approaches for electronic health records phenotyping: a methodical review.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Majid AfsharDivision of Pulmonary and Critical Care Medicine, Loyola University Medical Center, Maywood, IL.
Cara JoyceDepartment of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Anthony OakeyDepartment of Computer Science, Loyola University Chicago, Chicago, IL.
Perry FormanekDepartment of Medicine, Loyola University Medical Center, Maywood, IL.
Philip YangDepartment of Medicine, Loyola University Medical Center, Maywood, IL.
Matthew M ChurpekDivision of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL.
Richard S CooperDepartment of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Susan ZeliskoInformatics and Systems Development, Health Sciences Division, Loyola University Chicago, Maywood, IL.
Ron PriceInformatics and Systems Development, Health Sciences Division, Loyola University Chicago, Maywood, IL.
Dmitriy DligachDepartment of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.

Funding

CHANGE OF GRANTEE INSTITUTION 1 K23 AA024503 Alcohol, Burn-Injury, and Acute Respiratory Distress SyndromeK23AA024503 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI AFSHAR, MAJID · 2016 to 2020
$948k
NIAAA NIH HHS K23 AA024503
6 · The paper itself

Abstract

Acute Respiratory Distress Syndrome (ARDS) is a syndrome of respiratory failure that may be identified using text from radiology reports. The objective of this study was to determine whether natural language processing (NLP) with machine learning performs better than a traditional keyword model for ARDS identification. Linguistic pre-processing of reports was performed and text features were inputs to machine learning classifiers tuned using 10-fold cross-validation on 80% of the sample size and tested in the remaining 20%. A cohort of 533 patients was evaluated, with a data corpus of 9,255 radiology reports. The traditional model had an accuracy of 67.3% (95% CI: 58.3-76.3) with a positive predictive value (PPV) of 41.7% (95% CI: 27.7-55.6). The best NLP model had an accuracy of 83.0% (95% CI: 75.9-90.2) with a PPV of 71.4% (95% CI: 52.1-90.8). A computable phenotype for ARDS with NLP may identify more cases than the traditional model.

Indexed as

Electronic Health RecordsNatural Language ProcessingRadiography, ThoracicSupervised Machine LearningAdultAgedArea Under CurveCohort StudiesDiagnosis, Computer-AssistedFemaleHumansLength of StayMaleMiddle AgedPredictive Value of TestsRespiratory Distress Syndrome

Identifiers

PMID30815053
PMCPMC6371271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.