Evidence map›Paper›PMID 30815007›Full record

ArticleFrontiers in plant science2019

Cannabinoid Profiling of Hemp Seed Oil by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry.

Cinzia Citti, Pasquale Linciano, Sara Panseri, Francesca Vezzalini, Flavio Forni, Maria Angela Vandelli, Giuseppe Cannazza

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 145 citations in OpenAlex.

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  5. Derivation of a health-based guidance value for ΔEFSA journal. European Food Safety Authority · 2025
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  9. Nutrients and Bioactive Compounds fromInternational journal of molecular sciences · 2025
    Review
  10. Chemical Profiling of Polyphenolic Fraction ofPlants (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
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  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Hemp Seeds (Molecules (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cinzia CittiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Pasquale LincianoDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Sara PanseriDepartment of Health, Animal Science and Food Safety, University of Milan, Milan, Italy.
Francesca VezzaliniDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Flavio ForniDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Maria Angela VandelliDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Giuseppe CannazzaDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
University of Modena and Reggio Emilia · ITIstituto di Nanotecnologia · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemp seed oil is well known for its nutraceutical, cosmetic and pharmaceutical properties due to a perfectly balanced content of omega 3 and omega 6 polyunsaturated fatty acids. Its importance for human health is reflected by the success on the market of organic goods in recent years. However, it is of utmost importance to consider that its healthy properties are strictly related to its chemical composition, which varies depending not only on the manufacturing method, but also on the hemp variety employed. In the present work, we analyzed the chemical profile of ten commercially available organic hemp seed oils. Their cannabinoid profile was evaluated by a liquid chromatography method coupled to high-resolution mass spectrometry. Besides tetrahydrocannabinol and cannabidiol, other 30 cannabinoids were identified for the first time in hemp seed oil. The results obtained were processed according to an untargeted metabolomics approach. The multivariate statistical analysis showed highly significant differences in the chemical composition and, in particular, in the cannabinoid content of the hemp oils under investigation.

Indexed as

cannabinoidscannabinoids mass spectrahemphemp seed oilhigh-resolution mass spectrometry

Identifiers

PMID30815007
PMCPMC6381057
OpenAlexW2912537816

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.