Evidence map›Paper›PMID 30814909›Full record

ReviewReproductive medicine and biology2019

Clinical strategies for ART treatment of infertile women with advanced maternal age.

Koji Nakagawa, Keiji Kuroda, Rikikazu Sugiyama

Abstract readReview
In one paragraph

Review in Reproductive medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. EnhancingGynecology and minimally invasive therapy
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Koji NakagawaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.ORCID 0000-0003-0874-5894
Keiji KurodaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.
Rikikazu SugiyamaCenter for Reproductive Medicine and Implantation Research Sugiyama Clinic Shinjuku Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn ever-increasing number of women in our country with advanced maternal age are choosing to achieve pregnancy. This means effective strategies are needed for infertile patients. Questions arise, however, concerning the need for ovarian stimulation, and, if so, whether intracytoplasmic sperm injection (ICSI) is better than conventional insemination for those women who may have only one mature oocyte.

methodsWe evaluated our data to answer these questions. Herein, we also introduce our strategy for patients who show unsynchronized follicular growth. MAIN

findingsOvarian stimulation in ART treatment for patients with advanced maternal age has resulted in the achievement of higher pregnancy rates, and therefore, this form of stimulation is often selected. Based on our data, ICSI as an insemination procedure has not improved clinical pregnancy rates compared with conventional insemination and has actually decreased the clinical pregnancy rates.

conclusionIn this article, we reviewed and compared the protocols and strategies that are available to increase the number of developed embryos for the patients with advanced maternal age. We hope that this review will be helpful for both patients and clinicians.

Indexed as

advanced maternal ageconventional inseminationdouble OPUICSIovarian stimulation

Identifiers

PMID30814909
PMCPMC6378758

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.