Evidence map›Paper›PMID 30814834›Full record

ArticleJournal of global infectious diseases

Global Contributors to Antibiotic Resistance.

Aastha Chokshi, Ziad Sifri, David Cennimo, Helen Horng

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of global infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 304 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
304citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

304 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Mapping the oral resistome: a systematic review.Journal of medical microbiology · 2024
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  9. No role of antibiotics in patients with chest trauma requiring inter-costal drain: a pilot randomized controlled trial.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
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244 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Aastha ChokshiDepartment of Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
Ziad SifriDepartment of Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
David CennimoDepartment of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
Helen HorngDepartment of Pharmacy, University Hospital, Newark, New Jersey, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntibiotic-resistant infections have become increasingly prevalent nowadays. As a result, it is essential to examine the key socioeconomic and political factors which contribute to the rise in the prevalence of antibiotic resistance in developing and developed nations. This study aims to identify the various contributors to the development of antibiotic resistance in each type of nation.

methodsPUBMED was used to identify primary research, systematic reviews, and narrative reviews published before Jan 2017. Search terms included antibiotic resistance, antimicrobial resistance, superbugs, multidrug-resistant organisms, developing countries, developed countries. Publications from different countries were included to ensure generalizability. Publications were excluded if they didn't mention factors causing resistance, focused on the molecular basis of resistance, or if they were case reports. Publicly available reports from national and international health agencies were used.

resultsIn developing countries, key contributors identified included: (1) Lack of surveillance of resistance development, (2) poor quality of available antibiotics, (3) clinical misuse, and (4) ease of availability of antibiotics. In developed countries, poor hospital-level regulation and excessive antibiotic use in food-producing animals play a major role in leading to antibiotic resistance. Finally, research on novel antibiotics is slow ing down due to the lack of economic incentives for antibiotic research.

conclusionOverall, multiple factors, which are distinct for developing and developed countries, contribute to the increase in the prevalence of antibiotic resistance globally. The results highlight the need to improve the regulatory framework for antibiotic use and research globally.

Indexed as

Antibiotic resistancedeveloped countriesdeveloping countriessocioeconomic driving forces

Identifiers

PMID30814834
PMCPMC6380099

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.