Evidence map›Paper›PMID 30814820›Full record

ArticleAnnals of neurosciences2019

Exercise Improves Recognition Memory and Acetylcholinesterase Activity in the Beta Amyloid-Induced Rat Model of Alzheimer's Disease.

Mohammad Amin Farzi, Saeed Sadigh-Eteghad, Khadijeh Ebrahimi, Mahnaz Talebi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mohammad Amin FarziNeurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Saeed Sadigh-EteghadNeurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Khadijeh EbrahimiDepartment of Sports Science and Physical Education, Marand Branch, Islamic Azad University, Marand, Iran.
Mahnaz TalebiNeurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Tabriz University of Medical Sciences · IRImam Reza Hospital · IRIslamic Azad University of Marand · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA correlation between physical exercise and cognitive improvement has been found in Alzheimer's disease (AD). This study aimed to investigate the effects of aerobic and resistance exercise on the recognition memory and acetylcholinesterase (AChE) activity in beta amyloid (Aβ) model of AD in rat. MATERIALS AND

methodsFifty male 8-week-old Wistar rats (250-280 g) were divided into 5 groups (

resultsThere was no significant difference in memory index and AChE activity between the sham surgery and control groups (

conclusionAerobic and resistance exercise could improve recognition memory and decrease AChE activity in Aβ-induced AD in rats. The decrease in AChE activity may be one of the mechanisms by which exercise improves cognition and memory in AD.

Indexed as

AcetylcholinesteraseAerobic exerciseAlzheimer's diseaseBeta amyloidResistance exercise

Identifiers

PMID30814820
PMCPMC6388429
OpenAlexW2914026129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.