Evidence map›Paper›PMID 30814766›Full record

ArticleJournal of the Mississippi Academy of Sciences. Mississippi Academy of Sciences2018

LASER PROBE WITH INTEGRATED CONTACT COOLING FOR SUBSURFACE TISSUE THERMAL REMODELING.

Chun-Hung Chang, Nathaniel M Fried

Open access · greenAbstract read
In one paragraph

Article in Journal of the Mississippi Academy of Sciences. Mississippi Academy of Sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Chun-Hung ChangDepartment of Physics and Optical Science, University of North Carolina at Charlotte, USA.
Nathaniel M FriedDepartment of Physics and Optical Science, University of North Carolina at Charlotte, USA.
Optica · USUniversity of North Carolina at Charlotte · US

Funding

Minimally Invasive Laser Treatment of Female Stress Urinary IncontinenceR15DK099774 · NIDDK · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI FRIED, NATHANIEL M · 2014 to 2014
$434k
NIDDK NIH HHS R15 DK099774
6 · The paper itself

Abstract

Over 6.5 million women in the United States suffer from female stress urinary incontinence (SUI). Only ~200,000 women choose surgery. There may be a role for a non-surgical, minimally invasive procedure that provides thermal shrinkage/remodeling of submucosal collagen in the endopelvic fascia. This study describes design, characterization, and preliminary testing of a novel probe with integrated contact cooling for potential use in transvaginal laser treatment of SUI. Laser energy at a deeply penetrating, near-infrared wavelength of 1075 nm was delivered through a 600-μm-core fiber optic patchcord into a 90° side-firing probe head (19 × 22 mm) with integrated flow cell and sapphire window cooled to -2°C by circulating an alcohol-based solution. An inflatable balloon attached to the probe insured contact with vaginal wall. A force sensor and thermocouples monitored pressure and temperature. Thermal lesions were created in vaginal tissue of three cadavers (power = 4.6-6.4 W; spot diameter = 5.2 mm; time = 30 s). Thermal lesion areas measured 3.1-4.6 mm

Indexed as

cadaverlaserminimally invasivenonsurgicalremodelingstress urinary incontinencethermal

Identifiers

PMID30814766
PMCPMC6388701
OpenAlexW3025870919

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.