Evidence map›Paper›PMID 30814750›Full record

ArticleIndian journal of anaesthesia2019

Low-dose S+ ketamine in target-controlled intravenous anaesthesia with remifentanil and propofol for open gynaecological surgery: A randomised controlled trial.

Farida Binte Ithnin, Daryl Jian An Tan, Xue Lian Xu, Chin How Tan, Rehena Sultana, Ban Leong Sng

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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  17. Ketamine Use in the Surgical Patient: a Literature Review.Current pain and headache reports · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Farida Binte IthninDepartment of Women's Anaesthesia, KK Women's and Women's Hospital, Singapore.
Daryl Jian An TanDepartment of Women's Anaesthesia, KK Women's and Women's Hospital, Singapore.
Xue Lian XuDivision of Nursing, KK Women's and Children's Hospital, Singapore.
Chin How TanDepartment of Women's Anaesthesia, KK Women's and Women's Hospital, Singapore.
Rehena SultanaCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
Ban Leong SngDepartment of Women's Anaesthesia, KK Women's and Women's Hospital, Singapore.
KK Women's and Children's Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsUsing remifentanil-propofol target-controlled infusion (TCI) in open gynaecological surgeries could be associated with opioid-induced hyperalgesia postoperatively. This study's aim was to investigate the effect of low-dose S-ketamine compared with control on cumulative morphine consumption 24 h postoperatively in women undergoing open abdominal hysterectomy with remifentanil-propofol TCI technique.

methodsNinety female patients above 21 years old who underwent elective open abdominal hysterectomy under general anaesthesia with remifentanil-propofol TCI were recruited. They were randomised to receive either normal saline as control (

resultsThe cumulative 24-h morphine consumption postoperatively (

conclusionLow-dose S-ketamine did not reduce the total cumulative morphine consumption in patients undergoing major open gynaecological surgeries with remifentanil-propofol TCI.

Indexed as

Hysterectomyketaminepain

Identifiers

PMID30814750
PMCPMC6383487
OpenAlexW2976551206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.