Evidence map›Paper›PMID 30814661›Full record

ArticleScientific reports2019

Computer-aided diagnosis of colorectal polyps using linked color imaging colonoscopy to predict histology.

Min Min, Song Su, Wenrui He, Yiliang Bi, Zhanyu Ma, Yan Liu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04749277 (Artificial Intelligence in the Characterization of Small and Diminutive Colorectal Polyps), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04749277 completednot on this mapstarted 2021, after this paper: background citation

Artificial Intelligence in the Characterization of Small and Diminutive Colorectal Polyps: A Prospective Study in a Clinical Setting Using CAD EYE®

TypeobservationalSponsorUnidade Local de Saúde de Coimbra, EPERan2021 to 2021Enrolled197ConditionsColonic PolypsArmsCAD EYE® (Fujifilm, Europe, Gesellschaft mit beschränkter Haftung, Dusseldorf, Germany)
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Computer-aided diagnosis for colorectal polyp in comparison with endoscopists: Systematic review and meta-analysis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Artificial Intelligence in Endoscopy.Digestive diseases and sciences · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Artificial inelegance in endoscopy: An updated auricle of Delphi!Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Min MinDepartment of Gastroenterology and Hepatology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, 100071, China.
Song SuDepartment of Gastroenterology and Hepatology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, 100071, China.
Wenrui HePattern Recognition and Intelligent System Laboratory, School of Information and Communication Engineering, Beijing University of Posts and Telecommunications, Beijing, 100876, China.
Yiliang BiDepartment of Gastroenterology and Hepatology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, 100071, China.
Zhanyu MaPattern Recognition and Intelligent System Laboratory, School of Information and Communication Engineering, Beijing University of Posts and Telecommunications, Beijing, 100876, China. mazhanyu@bupt.edu.cn.ORCID 0000-0003-2950-2488
Yan LiuDepartment of Gastroenterology and Hepatology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, 100071, China. 13911798288@163.com.
Academy of Military Medical Sciences · CNBeijing University of Posts and Telecommunications · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed a computer-aided diagnosis (CAD) system based on linked color imaging (LCI) images to predict the histological results of polyps by analyzing the colors of the lesions. A total of 139 images of adenomatous polyps and 69 images of non-adenomatous polyps obtained from our hospital were collected and used to train the CAD system. A test set of LCI images, including both adenomatous and non-adenomatous polyps, was prospectively collected from patients who underwent colonoscopies between Oct and Dec 2017; this test set was used to assess the diagnostic abilities of the CAD system compared to those of human endoscopists (two experts and two novices). The accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of this novel CAD system for the training set were 87.0%, 87.1%, 87.0%, 93.1%, and 76.9%, respectively. The test set included 115 adenomatous polyps and 66 non-adenomatous polyps that were prospectively collected. The CAD system identified adenomatous or non-adenomatous polyps in the test set with an accuracy of 78.4%, a sensitivity of 83.3%, a specificity of 70.1%, a PPV of 82.6%, and an NPV of 71.2%. The accuracy of the CAD system was comparable to that of the expert endoscopists (78.4% vs 79.6%; p = 0.517). In addition, the diagnostic accuracy of the novices was significantly lower to the performance of the experts (70.7% vs 79.6%; p = 0.018). A novel CAD system based on LCI could be a rapid and powerful decision-making tool for endoscopists.

Indexed as

Adenomatous PolypsColonic PolypsColonoscopyColorectal NeoplasmsDiagnosis, Computer-AssistedFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedNarrow Band Imaging

Identifiers

PMID30814661
PMCPMC6393495
OpenAlexW2917951384

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.