ArticleScientific reports2019
Bovine leukemia virus DNA associated with breast cancer in women from South Brazil.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Viral Genomic Footprints in Breast Cancer: A Systematic Review and Meta-Analysis of Tissue-Based Detection of Epstein-Barr Virus and Bovine Leukemia Virus.International journal of molecular sciences · 2026Pooled it
- Bovine leukemia virus (BLV) and risk of breast cancer; a systematic review and meta-analysis.Retrovirology · 2024Pooled it
- Bovine leukemia virus relation to human breast cancer: Meta-analysis.Microbial pathogenesis · 2020Pooled it
- Article
- Absence of detectable bovine leukemia virus miRNAs in human cancer small RNA-seq datasets.Microbiology spectrum · 2026Article
- Article
- Association of the BoLA-DRB3*12:01 allele with resistance to bovine leukosis virus infection in Crioula Lageana cattle.Journal of applied genetics · 2026Article
- Establishment and Characterization of Human Cell Lines Stably Infected With Bovine Leukemia Virus In Vitro Reveals Apoptosis After Latency and Silencing.Transboundary and emerging diseases · 2026Article
- DNA porcine viruses detected on fresh liver samples destined for human consumption.Veterinary research communications · 2025Article
- Infectivity and persistence of bovine leukemia virus in human breast cells: assessing a possible zoonotic link to cancer.Veterinary research communications · 2025Article
- Bovine Leukemia Virus and Human Breast Cancer: A Review of Clinical and Molecular Evidence.Viruses · 2025Review
- Human Cytomegalovirus Infection and Breast Cancer: A Literature Review of Clinical and Experimental Data.Biology · 2025Review
- Bovine leukemia virus: an emerging concern for zoonotic cross-species transmission.Frontiers in cellular and infection microbiology · 2025Review
- Triple Viral Infections in Advanced Breast Cancer: Insights from a Three-Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2024Article
- The transmission of bovine leukemia virus to calves occurs mostly through colostrum and milk.Veterinary world · 2024Article
- The Prevalence and Molecular Characterization of Bovine Leukemia Virus among Dairy Cattle in Henan Province, China.Viruses · 2024Article
- The viral origins of breast cancer.Infectious agents and cancer · 2024Review
- The Role of Oncogenic Viruses in the Pathogenesis of Sporadic Breast Cancer: A Comprehensive Review of the Current Literature.Pathogens (Basel, Switzerland) · 2024Review
- Design and implementation of a TaqManVeterinary research forum : an international quarterly journal · 2024Article
- Investigation of the target genes of BLV miRNAs and the expression levels of miR-B4-3p and miR-B2-5p in cattle infected with Bovine Leukemia Virus.Veterinary research forum : an international quarterly journal · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is a neoplastic condition with a high morbidity and mortality amongst women worldwide. Recent data linking bovine leukemia virus (BLV) with breast cancer has been contested already. Our study investigated the presence of BLV genome in healthy (n = 72) and cancerous (n = 72) paraffin-embedded samples of breast tissues from women in south Brazil. BLV DNA was found most frequently (30.5%) in breast cancer tissue than in healthy breast (13.9%) (Odds ratio = 2.73; confidence interval = 1.18-6.29; p = 0.027). In contrast, antibodies to BLV were found in a very small percentage of healthy blood donors. There was no association between BLV DNA and other tumor prognostic biological markers such as hormonal receptors, HER2 oncoprotein, proliferation index, metastasis in sentinels lymph nodes, and tumor grade and size. Our findings suggest that BLV should be considered a potential predisposing factor to breast cancer in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.