Evidence map›Paper›PMID 30814556›Full record

ArticleScientific reports2019

Hydration shell differentiates folded and disordered states of a Trp-cage miniprotein, allowing characterization of structural heterogeneity by wide-line NMR measurements.

Nóra Taricska, Mónika Bokor, Dóra K Menyhárd, Kálmán Tompa, András Perczel

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nóra TaricskaLaboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Budapest, 1117, Hungary.
Mónika BokorInstitute for Solid State Physics and Optics, Wigner RCP of the HAS, 1121, Budapest, Hungary.ORCID 0000-0001-8883-1316
Dóra K MenyhárdMTA-ELTE Protein Modelling Research Group, Pázmány Péter st. 1A, 1117, Budapest, Hungary.
Kálmán TompaInstitute for Solid State Physics and Optics, Wigner RCP of the HAS, 1121, Budapest, Hungary.
András PerczelLaboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Budapest, 1117, Hungary. perczel@chem.elte.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydration properties of folded and unfolded/disordered miniproteins were monitored in frozen solutions by wide-line

Indexed as

FreezingIceProtein FoldingBacteriaMolecular Dynamics SimulationNuclear Magnetic Resonance, BiomolecularProtein DenaturationProtein Structure, TertiaryRecombinant ProteinsThermodynamicsIceRecombinant ProteinsTC5b protein, synthetic

Identifiers

PMID30814556
PMCPMC6393587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.