ArticleNature communications2019
Man-made microbial resistances in built environments.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 1 synthesis or guideline pooled it, 207 citations in OpenAlex.
- [Is Disinfection of Public Surfaces useful for the Prevention of SARS-CoV-2 Infections?]Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2021Pooled it
- Beyond Infection-Indoor Airborne Pathogens as Contributors to Respiratory Inflammation and Immune Dysregulation: A Narrative Review.Pathogens (Basel, Switzerland) · 2026Review
- Strain transmission links human microbiomes along the oral-gut axis and across cohabiting individuals.Cell press blue · 2026Article
- Genomic Epidemiology of Antibiotic-Resistant Bacteria Sampled from Metropolitan Wastewater.Microorganisms · 2026Article
- Article
- Plasmidome, resistome, and virulence-associated gene characterization ofMicrobiology spectrum · 2026Article
- Household environmental characteristics influence the house dust metagenome.Environmental research · 2026Article
- Recent Microbial Evolutionary Insights From Metagenomics.Genome biology and evolution · 2026Review
- Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance.npj antimicrobials and resistance · 2026Article
- Complex compositional and metabolic response of river sediment microbiomes to multiple anthropogenic stressors.ISME communications · 2026Article
- Surface Contamination by Multidrug-Resistant Gram-Negative Bacteria in a Healthcare Facility: Resistance Determinants and Biofilm-Associated Adhesion.International journal of microbiology · 2026Article
- Bacterial resistance across habitats: from German schools to the International Space Station.Frontiers in microbiology · 2026Article
- Metagenomic analysis of the nasopharyngeal microbiomes and resistomes in asthma, COVID-19 infected, and healthy individuals.Frontiers in microbiology · 2026Article
- Genome-resolved surveillance and predictive ecological risk modeling of urban microbiomes.Microbiome · 2025Article
- Targeted probe capture metagenomics-enabled surveillance of multidrug-resistant organisms and antimicrobial resistance genes in post-handwashing areas of public washrooms.Environmental microbiome · 2025Article
- Unravelling the impacts of captivity on saltwater crocodile (Crocodylus porosus) cloacal bacterial communities and physiology.FEMS microbiology ecology · 2025Article
- Touching Surfaces - Presence of microorganisms on antimicrobial metal surfaces on the International Space Station and in German schools.BMC microbiology · 2025Article
- Article
- "Dusting Off the Cobwebs": Rethinking How We Use New Antibiotics.Antibiotics (Basel, Switzerland) · 2025Review
- Probiotic-Based Approaches for Sustainable Control of Infectious Risk in Mass Transport: Current Data and Future Perspectives.Microbial biotechnology · 2025Review
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial resistance is a serious threat to global public health, but little is known about the effects of microbial control on the microbiota and its associated resistome. Here we compare the microbiota present on surfaces of clinical settings with other built environments. Using state-of-the-art metagenomics approaches and genome and plasmid reconstruction, we show that increased confinement and cleaning is associated with a loss of microbial diversity and a shift from Gram-positive bacteria, such as Actinobacteria and Firmicutes, to Gram-negative such as Proteobacteria. Moreover, the microbiome of highly maintained built environments has a different resistome when compared to other built environments, as well as a higher diversity in resistance genes. Our results highlight that the loss of microbial diversity correlates with an increase in resistance, and the need for implementing strategies to restore bacterial diversity in certain built environments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.