ArticleJournal of Alzheimer's disease : JAD2019
Complex Walking Tasks and Risk for Cognitive Decline in High Functioning Older Adults.
Article in Journal of Alzheimer's disease : JAD, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Measurement properties of the usual and fast gait speed tests in community-dwelling older adults: a COSMIN-based systematic review.Age and ageing · 2024Pooled it
- Gait in cerebral small vessel disease, pre-dementia, and dementia: A systematic review.International journal of stroke : official journal of the International Stroke Society · 2023Pooled it
- Dual-Task Gait as a Predictive Tool for Cognitive Impairment in Older Adults: A Systematic Review.Frontiers in aging neuroscience · 2021Pooled it
- Associations between Finger-Dexterity Dual Task and Neuropsychological Tests in Middle-Aged and Older Adults.Annals of geriatric medicine and research · 2026Article
- Gait Analysis for Identifying Normal Cognition, Subjective Cognitive Decline, and Mild Cognitive Impairment in Parkinson Disease: Diagnostic Study.JMIR mHealth and uHealth · 2026Article
- Article
- Gait, balance, and physical performance as markers of early Alzheimer's disease and related dementia risk.Journal of Alzheimer's disease : JAD · 2025Article
- Nigrostriatal dopaminergic integrity in relation to prefrontal cortex activity and gait performance during dual-task walking in older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- The Longitudinal Relationship Between Physical Functions and Cognitive Functions Among Middle-Aged and Older Adults in Primary Care.International journal of environmental research and public health · 2025Article
- Wearable sensors and machine learning fusion-based fall risk prediction in covert cerebral small vessel disease.Frontiers in neuroscience · 2025Article
- Remote Digital Technologies for the Early Detection and Monitoring of Cognitive Decline in Patients With Type 2 Diabetes: Insights From Studies of Neurodegenerative Diseases.Journal of diabetes science and technology · 2024Review
- The bidirectional associations between sarcopenia-related traits and cognitive performance.Scientific reports · 2024Article
- Detecting cognitive decline in high-functioning older adults: The relationship between subjective cognitive concerns, frequency of high neuropsychological test scores, and the frontoparietal control network.Journal of the International Neuropsychological Society : JINS · 2024Article
- Uneven surface and cognitive dual-task independently affect gait quality in older adults.Gait & posture · 2023Article
- Novel automaticity index reveals a cognitive ability-related decline in gait automaticity during dual-task walking.bioRxiv : the preprint server for biology · 2023Article
- Sarcopenia-defining parameters, but not sarcopenia, are associated with cognitive domains in middle-aged and older European men.Journal of cachexia, sarcopenia and muscle · 2023Article
- Does tandem balance test predict cognitive impairment among older adults? Findings from Longitudinal Ageing Study in India, 2017-18.Aging clinical and experimental research · 2023Article
- Walking pace, handgrip strength, age, APOE genotypes, and new-onset dementia: the UK Biobank prospective cohort study.Alzheimer's research & therapy · 2023Article
- Cognitive-motor interventions based on virtual reality and instrumental activities of daily living (iADL): an overview.Frontiers in aging neuroscience · 2023Review
- Novel attentional gait index reveals a cognitive ability-related decline in gait automaticity during dual-task walking.Frontiers in aging neuroscience · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundPerformance on complex walking tasks may provide a screen for future cognitive decline.
objectiveTo identify walking tasks that are most strongly associated with subsequent cognitive decline.
methodsCommunity-dwelling older adults with Modified Mini-Mental State (3MS) >85 at baseline (n = 223; mean age = 78.7, 52.5% women, 25.6% black) completed usual-pace walking and three complex walking tasks (fast-pace, narrow-path, visuospatial dual-task). Slope of 3MS scores for up to 9 subsequent years (average = 5.2) were used to calculate a cognitive maintainer (slope ≥0) or decliner (slope <0) outcome variable. Logistic regression models assessed associations between gait speeds and being a cognitive decliner. A sensitivity analysis in a subsample of individuals (n = 66) confirmed results with adjudicated mild cognitive impairment (MCI) or dementia at 8-9 years post-walking assessment.
resultsCognitive decliners were 52.5% of the sample and on average were slower for all walking tasks compared to maintainers. In models adjusted for demographic and health variables, faster fast-pace (OR = 0.87 per 0.1 m/s, 95% CI: 0.78, 0.97) and dual-task (OR = 0.84 per 0.1 m/s, 95% CI: 0.73, 0.96) gait speeds were associated with lower likelihood of being a cognitive decliner. Usual-pace gait speed was not associated (OR = 0.96 per 0.1 m/s, 95% CI: 0.85, 1.08). Results were nearly identical in analyses with adjudicated MCI or dementia as the outcome.
conclusionFast-pace and dual-task walking may provide simple and effective tools for assessing risk for cognitive decline in older individuals with high cognitive function. Such screening tools are important for strategies to prevent or delay onset of clinically meaningful change.
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Registered trials
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