Evidence map›Paper›PMID 30814319›Full record

ArticlemSphere2019

Secretory Microneme Proteins Induce T-Cell Recall Responses in Mice Chronically Infected with Toxoplasma gondii.

Iti Saraav, Qiuling Wang, Kevin M Brown, L David Sibley

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. HarnessingAnnals of medicine · 2026
    Review
  3. Article
  4. Article
  5. Identification and Characterization ofMicrobiology spectrum · 2021
    Article
  6. Diverse Roles of TgMIC1/4/6 in theFrontiers in microbiology · 2021
    Review
  7. Article
  8. Vaccines · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Iti SaraavDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Qiuling WangDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Kevin M BrownDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
L David SibleyDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA sibley@wustl.edu.
Washington University in St. Louis · US

Funding

Molecular Basis of Human ToxoplasmosisR01AI118426 · NIAID · WASHINGTON UNIVERSITY · PI SIBLEY, L. DAVID · 2015 to 2024
$6.0M
MOLECULAR BASIS OF TOXOPLASMOSIS IN AIDS PATIENTSR01AI036629 · NIAID · WASHINGTON UNIVERSITY · PI SIBLEY, L. DAVID · 1994 to 2013
$5.3M
NIAID NIH HHS R01 AI036629NIAID NIH HHS R01 AI118426
6 · The paper itself

Abstract

Microneme (MIC) proteins play important roles in the recognition, adhesion, and invasion of host cells by

Indexed as

Immunologic MemoryAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell Adhesion MoleculesChronic DiseaseFemaleImmunity, CellularInterferon-gammaMiceMice, Inbred BALB CMice, Inbred C57BLProtozoan ProteinsSpecific Pathogen-Free OrganismsT-LymphocytesToxoplasmaCell Adhesion MoleculesInterferon-gammaMIC1 protein, Toxoplasma gondiiMIC3 protein, Toxoplasma gondiiMIC4 protein, Toxoplasma gondiiMIC6 protein, Toxoplasma gondiiProtozoan Proteinsantigen-specific T cellsgamma interferon detection assaysmemory T cellsmicroneme antigensrecall responsetoxoplasmosis

Identifiers

PMID30814319
PMCPMC6393730
OpenAlexW2916718824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.