Evidence map›Paper›PMID 30814271›Full record

ArticlePediatrics2019

Early Use of Anti-influenza Medications in Hospitalized Children With Tracheostomy.

Ryo Miyakawa, Nicolas B Barreto, Roberta M Kato, Michael N Neely, Christopher J Russell

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Antiviral Use Among Children Hospitalized With Laboratory-Confirmed Influenza Illness: A Prospective, Multicenter Surveillance Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  5. Review
  6. Article
  7. Guideline-Concordant Antiviral Treatment in Children at High Risk for Influenza Complications.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ryo MiyakawaDivisions of Pediatric Pulmonology and Sleep Medicine.
Nicolas B BarretoDepartment of Psychology, Claremont Graduate University, Claremont, California; and.
Roberta M KatoDivisions of Pediatric Pulmonology and Sleep Medicine.
Michael N NeelyDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California.
Christopher J RussellDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California crussell@chla.usc.edu.
Pulmonary Associates · USChildren's Hospital of Los Angeles · USClaremont Graduate University · USUniversity of Southern California · US

Funding

Southern California Clinical and Translational Science InstituteKL2TR000131 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$2.1M
NCATS NIH HHS KL2 TR000131
6 · The paper itself

Abstract

backgroundEarly administration of anti-influenza medications is recommended for all children hospitalized with influenza. We investigated whether early use of anti-influenza medications is associated with improved outcomes in children with tracheostomy hospitalized with influenza.

methodsWe performed a multicenter retrospective cohort study through the Pediatric Health Information System database for patients aged 30 days to 19 years who were discharged between October 1, 2007, and September 30, 2015 with diagnostic codes for both influenza and tracheostomy. Our primary predictor was receipt of anti-influenza medications on hospital day 0 or 1. We used propensity score matching to adjust for confounding by indication. Primary outcomes were length of stay (LOS) and 30-day all-cause revisit rate (emergency department visit or hospital admission).

resultsOf 1436 discharges screened, 899 met inclusion criteria. The median admission age was 5 years (interquartile range: 2-10). The majority had multiple complex chronic conditions (median 3; interquartile range: 3-4) and technology dependence, such as gastrostomy tube (73.6%). After matching 772 unique admissions by propensity score, LOS was shorter for the cohort receiving early anti-influenza medications (6.4 vs 7.5 days;

conclusionsEarly use of anti-influenza medications in children with tracheostomy hospitalized with influenza is associated with shorter LOS, but these children continue to receive antibiotics despite identification and treatment of their viral infections.

Indexed as

Child, HospitalizedAdolescentAntiviral AgentsChildChild, PreschoolCohort StudiesFemaleHumansInfantInfluenza, HumanMaleRetrospective StudiesTime FactorsTracheostomyYoung AdultAntiviral Agents

Identifiers

PMID30814271
PMCPMC6398370
OpenAlexW2916121731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.