Evidence map›Paper›PMID 30814138›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2019

Women and COPD: do we need more evidence?

Christophe Gut-Gobert, Arnaud Cavaillès, Adrien Dixmier, Stéphanie Guillot, Stéphane Jouneau, Christophe Leroyer, Sylvain Marchand-Adam, David Marquette, Jean-Claude Meurice, Nicolas Desvigne and 3 more

Open access · diamondAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 3 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 3 syntheses or guidelines pooled it, 153 citations in OpenAlex.

  1. Pooled it
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  14. Sex, hormones, and lung health.Physiological reviews · 2026
    Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 1 country.

Christophe Gut-GobertG.E.T.B.O. (Groupe d'Etude de la Thrombose de Bretagne Occidentale), Université Européenne de Bretagne, Université de Brest, EA3878, IFR148, Hôpital La Cavale Blanche, Département de Médecine Interne et Pneumologie, Brest, France.
Arnaud CavaillèsInstitut du Thorax, CHU de Nantes, Dept of Pulmonology, Nantes, France.
Adrien DixmierDept of Pulmonology, Orléans Regional Hospital, Orléans, France.
Stéphanie GuillotUnité d'Explorations Fonctionnelles Respiratoires, CHRU Rennes, Rennes, France.
Stéphane JouneauService de Pneumologie, Hôpital Pontchaillou, Rennes, France.
Christophe LeroyerG.E.T.B.O. (Groupe d'Etude de la Thrombose de Bretagne Occidentale), Université Européenne de Bretagne, Université de Brest, EA3878, IFR148, Hôpital La Cavale Blanche, Département de Médecine Interne et Pneumologie, Brest, France.
Sylvain Marchand-AdamUniversité François Rabelais Faculté de Médecine de Tours, Inserm 1100, CHRU de Tours Service de Pneumologie, Tours, France.
David MarquetteDept of Pulmonary Medicine, Centre Hospitalier Bretagne Atlantique, Vannes, France.
Jean-Claude MeuriceDept of Pulmonology Centre Hospitalier de l'Université de Poitiers, Poitiers, France.
Nicolas DesvigneNovartis Pharma, Scientific Operations, Rueil-Malmaison, France.
Hugues MorelDept of Pulmonology, Orléans Regional Hospital, Orléans, France.
Christine Person-TacnetDept of Pulmonology, CHU Angers, Angers, France.
Chantal RaherisonService des Maladies Respiratoires, CHU Bordeaux, Epicene U1219 Université de Bordeaux, Bordeaux, France.
Centre hospitalier universitaire d'Orléans · FRUniversité Européenne de Bretagne · FRCentre hospitalier Bretagne Atlantique · FRCentre Hospitalier Universitaire d'Angers · FRCentre Hospitalier Universitaire de Nantes · FRCentre Hospitalier Universitaire de Rennes · FRInstitut de Recherche en Santé, Environnement et Travail · FRNovartis (France) · FRUniversité de Bordeaux · FRUniversité de Poitiers · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasingly female face of chronic obstructive pulmonary disease (COPD) prevalence among women has equalled that of men since 2008, due in part to increased tobacco use among women worldwide and exposure to biomass fuels. This finding is supported by a number of characteristics. There is evidence of susceptibility to smoking and other airborne contaminants, along with epidemiological and phenotypic manifestations. COPD has thus become the leading cause of death in women in the USA. The clinical presentation is characterised by increasingly pronounced dyspnoea with a marked tendency towards anxiety and depression, undernutrition, nonsmall cell lung cancer (especially adenocarcinoma) and osteoporosis. Quality of life is also more significantly impacted. The theories advanced to explain these differences involve the role played by oestrogens, impaired gas exchange in the lungs and smoking habits. While these differences require appropriate therapeutic responses (smoking cessation, pulmonary rehabilitation, long-term oxygen therapy), barriers to the treatment of women with COPD include greater under-diagnosis than in men, fewer spirometry tests and medical consultations. Faced with this serious public health problem, we need to update and adapt our knowledge to the epidemiological changes.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesPulmonary Disease, Chronic ObstructiveAdolescentAdultAgedAged, 80 and overAge FactorsCost of IllnessFemaleHumansLungMaleMiddle AgedPhenotypePrevalence

Identifiers

PMID30814138
PMCPMC9488562
OpenAlexW2920521833

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.