Evidence map›Paper›PMID 30814119›Full record

ArticleDevelopment (Cambridge, England)2019

Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis.

Swetansu K Hota, Jeffrey R Johnson, Erik Verschueren, Reuben Thomas, Aaron M Blotnick, Yiwen Zhu, Xin Sun, Len A Pennacchio, Nevan J Krogan, Benoit G Bruneau

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. SMARCD1 and Its Functional Relevance in SWI/SNF and Cancer.International journal of molecular sciences · 2026
    Review
  4. Article
  5. G protein GαThe Journal of biological chemistry · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. The molecular mechanisms of cardiac development and related diseases.Signal transduction and targeted therapy · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Swetansu K HotaGladstone Institutes, San Francisco, CA 94158, USA.
Jeffrey R JohnsonGladstone Institutes, San Francisco, CA 94158, USA.
Erik VerschuerenGladstone Institutes, San Francisco, CA 94158, USA.
Reuben ThomasGladstone Institutes, San Francisco, CA 94158, USA.
Aaron M BlotnickGladstone Institutes, San Francisco, CA 94158, USA.
Yiwen ZhuGenomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Xin SunDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK.
Len A PennacchioGenomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Nevan J KroganGladstone Institutes, San Francisco, CA 94158, USA.
Benoit G BruneauGladstone Institutes, San Francisco, CA 94158, USA benoit.bruneau@gladstone.ucsf.edu.ORCID 0000-0002-0804-7597
Gladstone Institutes · USUnited States Department of Energy · USUniversity of Oxford · GB

Funding

Generation of an In Vivo Human Genome Transcriptional Enhancer DatasetR01HG003988 · NHGRI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Len Alexander Pennacchio · 2006 to 2026
$24.1M
Transcriptional Networks During Cardiac DifferentiationP01HL089707 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI SRIVASTAVA, DEEPAK · 2008 to 2017
$20.4M
Project 3: Control of cardiac transcription by MEF2 and myocardinP01HL146366 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI SRIVASTAVA, DEEPAK · 2019 to 2023
$13.7M
MOLECULAR AND CELLULAR BASIS OF CARDIOVASCULAR DISEASET32HL007731 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Brian L Black · 1992 to 2026
$12.4M
In Vivo Characterization of Major ENCODE-Predicted Classes of Noncoding ElementsUM1HG009421 · NHGRI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PENNACCHIO, LEN ALEXANDER, VISEL, AXEL · 2017 to 2021
$6.8M
The Epigenetic Landscape of Heart DevelopmentUM1HL098179 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BRUNEAU, BENOIT GAETAN, POLLARD, KATHERINE S. · 2015 to 2019
$4.7M
Genome-Wide Resources for Transcriptional Enhancers Active in the Human HeartR24HL123879 · NHLBI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PENNACCHIO, LEN ALEXANDER, VISEL, AXEL · 2015 to 2019
$3.9M
Chromatin remodeling complexes in heart developmentR01HL085860 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BRUNEAU, BENOIT GAETAN · 2006 to 2010
$2.3M
NHGRI NIH HHS R01 HG003988NHGRI NIH HHS UM1 HG009421NHLBI NIH HHS P01 HL089707NHLBI NIH HHS P01 HL146366NHLBI NIH HHS R01 HL085860NHLBI NIH HHS R24 HL123879NHLBI NIH HHS T32 HL007731NHLBI NIH HHS UM1 HL098179
6 · The paper itself

Abstract

Chromatin remodeling complexes instruct cellular differentiation and lineage specific transcription. The BRG1/BRM-associated factor (BAF) complexes are important for several aspects of differentiation. We show that the catalytic subunit gene

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsCell DifferentiationChromatinChromatin Assembly and DisassemblyDNA HelicasesGenomeHeartMiceMultiprotein ComplexesMyocytes, CardiacNuclear ProteinsOrganogenesisProtein BindingProtein SubunitsTime FactorsChromatinDNA HelicasesMultiprotein ComplexesNuclear ProteinsProtein SubunitsSmarca4 protein, mouseTranscription FactorsChromatinDifferentiationGene regulationHeart

Identifiers

PMID30814119
PMCPMC6803373
OpenAlexW2915522209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.