Evidence map›Paper›PMID 30813859›Full record

ArticleInternational journal of STD & AIDS2019

Cervical cancer awareness and presence of abnormal cytology among HIV-infected women on antiretroviral therapy in rural Andhra Pradesh, India.

Sanghyuk S Shin, Catherine L Carpenter, Maria L Ekstrand, Qiao Wang, Surbhi Grover, Nicola M Zetola, Kartik Yadav, Sanjeev Sinha, Adeline M Nyamathi

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sanghyuk S Shin1 Sue & Bill Gross School of Nursing, University of California, Irvine, CA, USA.
Catherine L Carpenter2 School of Nursing, University of California, Los Angeles, CA, USA.
Maria L Ekstrand3 Center for AIDS Prevention Studies, University of California, San Francisco, CA, USA.
Qiao Wang1 Sue & Bill Gross School of Nursing, University of California, Irvine, CA, USA.
Surbhi Grover4 Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Nicola M Zetola4 Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kartik Yadav1 Sue & Bill Gross School of Nursing, University of California, Irvine, CA, USA.
Sanjeev Sinha6 Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Adeline M Nyamathi1 Sue & Bill Gross School of Nursing, University of California, Irvine, CA, USA.ORCID 0000-0003-4979-6620

Funding

Asha Improving Health and Nutrition of Indian Women with AIDS and Their ChildrenR01MH098728 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EKSTRAND, MARIA L., NYAMATHI, ADELINE M · 2013 to 2017
$2.9M
Prognostic value of quantitative HPV viral load in determining cervical cancer treatment response and recurrenceK08CA230170 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GROVER, SURBHI · 2019 to 2023
$1.4M
The Effect of Mixed-strain Mycobacterium tuberculosis Infections on TB Treatment Outcomes in Botswana: A Retrospective Cohort Study.K01AI118559 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIN, SANGHYUK SAM · 2015 to 2019
$670k
NCI NIH HHS K08 CA230170NIAID NIH HHS K01 AI118559NIMH NIH HHS R01 MH098728
6 · The paper itself

Abstract

Cervical cancer is a leading cause of death among women in low- and middle-income countries, and women living with HIV are at high risk for cervical cancer. The objective of this study was to estimate the prevalence and correlates of cervical cancer and pre-cancer lesions and to examine cervical cancer knowledge among women living with HIV receiving antiretroviral therapy in rural Andhra Pradesh, India. We conducted cytology-based screening and administered a standardized questionnaire among 598 HIV-infected women. We found 5 (0.8%), 39 (6.5%), 29 (4.9%), and 4 (0.7%) had atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL), and squamous cervical carcinoma (SCC), respectively. In multivariable logistic regression analysis, ASCUS/LSIL was independently associated with age >16 years old at first sexual encounter and smokeless tobacco use. We found no factors associated with HSIL/SCC. In total, 101 women (16.9%) had heard of cervical cancer and 28 (27.7%) of them correctly identified HIV infection as a risk factor. In light of the high prevalence of pre-cancer lesions and low level of cervical cancer knowledge in our study population, focused interventions are needed to improve cervical cancer literacy and prevention among rural women living with HIV.

Indexed as

AdolescentAdultCarcinoma, Squamous CellFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansIndiaMiddle AgedPapanicolaou TestPapillomaviridaePapillomavirus InfectionsPrevalenceRisk FactorsRural PopulationSquamous Intraepithelial Lesions of the CervixcytologyFemalelesionprevalenceprevention

Identifiers

PMID30813859
PMCPMC6510620

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.