Evidence map›Paper›PMID 30813777›Full record

ArticleCNS oncology2019

A case report of high-grade astroblastoma in a young adult.

Sagar Bhalerao, Rajnish Nagarkar, Aditya Adhav

Open access · goldAbstract readCase Reports
In one paragraph

Article in CNS oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sagar BhaleraoDepartment of Medical Oncology, HCG Manavata Cancer Centre, Nashik, India.
Rajnish NagarkarDepartment of Surgical Oncology, HCG Manavata Cancer Centre, Nashik, India.
Aditya AdhavDepartment of Surgical Oncology, HCG Manavata Cancer Centre, Nashik, India.
HCG Cancer Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astroblastoma is an uncommon neuroepithelial primary tumor of the brain which is of uncertain origin. We present a case of high-grade astroblastoma in an 18-year-old female with a severe headache, loss of appetite, vomiting and generalized weakness. The patient had undergone a right frontoparietal craniotomy. Large subfalcine meningioma was excised. The lesion was suspected to be a meningioma. Primary radiological investigation revealed a 6.8 cm × 5.8 cm × 5.4 cm lesion. Although the radiological and intraoperative findings were of an extra-axial tumor, the histology and immunophenotype was of an astroblastoma. The patient was treated with cyclophosphamide, cisplatin and etoposide chemotherapy regimen. The patient was later treated with bi-weekly bevacizumab. The patient had improved symptomatically post-chemotherapy. However, there was no significant difference in lesion size. The patient died after 2 weeks. The prognosis of patients with astroblastoma is extremely poor as observed in our case.

Indexed as

AdolescentBrainBrain NeoplasmsDiagnosis, DifferentialFatal OutcomeFemaleHumansNeoplasm GradingNeoplasms, Neuroepithelialastroblastomabrain neoplasmbrain tumormagentic resonance imaging

Identifiers

PMID30813777
PMCPMC6499014
OpenAlexW2919418566

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.