Evidence map›Paper›PMID 30813620›Full record

ReviewGenes2019

Transcriptome Profiling and Molecular Therapeutic Advances in Cystic Fibrosis: Recent Insights.

Justin E Ideozu, Xi Zhang, Susanna McColley, Hara Levy

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Justin E IdeozuAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA. justin.ideozu@northwestern.edu.
Xi ZhangAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA. XiZhang@luriechildrens.org.
Susanna McColleyAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA. SMcColley@luriechildrens.org.ORCID 0000-0003-0842-728X
Hara LevyAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA. HLevy@luriechildrens.org.
Northwestern University · US

Funding

Integration of Genomics with Genetics - Molecular Phenotypes for CF Lung DiseaseDP2OD007031 · OD · MEDICAL COLLEGE OF WISCONSIN · PI LEVY, HARA · 2010 to 2010
$2.2M
NIH HHS DP2OD007031
6 · The paper itself

Abstract

In cystic fibrosis (CF), mutations in the cystic fibrosis transmembrane conductance regulator (

Indexed as

Cystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksGenetic Predisposition to DiseaseHumansMolecular Targeted TherapyCFTR protein, humanCystic Fibrosis Transmembrane Conductance Regulatorcystic fibrosismicroarraymolecular therapyRNA-Seqtranscriptome profiling

Identifiers

PMID30813620
PMCPMC6470978
OpenAlexW2915685810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.