Evidence map›Paper›PMID 30813608›Full record

ArticleInternational journal of molecular sciences2019

Epigenome-Wide Association Study (EWAS) of Blood Lipids in Healthy Population from STANISLAS Family Study (SFS).

Ting Xie, Vesna Gorenjak, Maria G Stathopoulou, Sébastien Dadé, Eirini Marouli, Christine Masson, Helena Murray, John Lamont, Peter Fitzgerald, Panagiotis Deloukas and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Multi-omics in Crohn's disease: New insights from inside.Computational and structural biotechnology journal · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ting XieUniversité de Lorraine, Inserm, IGE-PCV, 54000 Nancy, France. ting.xie@inserm.fr.ORCID 0000-0002-2585-8578
Vesna GorenjakUniversité de Lorraine, Inserm, IGE-PCV, 54000 Nancy, France. gorenjak.vesna@gmail.com.
Maria G StathopoulouUniversité de Lorraine, Inserm, IGE-PCV, 54000 Nancy, France. maria.stathopoulou@inserm.fr.
Sébastien DadéUniversité de Lorraine, Inserm, IGE-PCV, 54000 Nancy, France. sebastien.dade@univ-lorraine.fr.
Eirini MarouliQueen Mary University of London, E1 4NS London, UK. e.marouli@qmul.ac.uk.ORCID 0000-0001-6179-1609
Christine MassonUniversité de Lorraine, Inserm, IGE-PCV, 54000 Nancy, France. christine.masson@univ-lorraine.fr.
Helena MurrayRandox Laboratories Ltd, Crumlin, BT29 4XL County Antrim, UK. helena.murray@randox.com.
John LamontRandox Laboratories Ltd, Crumlin, BT29 4XL County Antrim, UK. john.lamont@randox.com.
Peter FitzgeraldRandox Laboratories Ltd, Crumlin, BT29 4XL County Antrim, UK. peter.fitzgerald@randox.com.
Panagiotis DeloukasQueen Mary University of London, E1 4NS London, UK. p.deloukas@qmul.ac.uk.
Sophie Visvikis-SiestUniversité de Lorraine, Inserm, IGE-PCV, 54000 Nancy, France. sophie.visvikis-siest@inserm.fr.

Funding

British Heart Foundation RG/14/5/30893
6 · The paper itself

Abstract

Epigenome-Wide Association Studies (EWAS) are furthering our knowledge of epigenetic modifications involved in the regulation of lipids' metabolism. Furthermore, epigenetic patterns associated with lipid levels may play an important role in predicting the occurrence of cardiovascular events. To further investigate the relationship between methylation status and lipids, we performed an EWAS in 211 individuals from the STANISLAS Family study (SFS). Methylation at two CpG sites (

Indexed as

Epigenesis, GeneticGenome-Wide Association StudyAdipose TissueComputational BiologyCpG IslandsDNA MethylationFamilyGenetic VariationHumansLipidsPromoter Regions, GeneticReproducibility of ResultsLipidsadipose tissueDNA methylationdyslipidemiasepigeneticsEWASgene Expression/polymorphismsgeneticslipids

Identifiers

PMID30813608
PMCPMC6429274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.