Evidence map›Paper›PMID 30813559›Full record

ArticleSensors (Basel, Switzerland)2019

Two-layer Electrospun System Enabling Wound Exudate Management and Visual Infection Response.

Mohamed Basel Bazbouz, Giuseppe Tronci

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohamed Basel BazbouzTextile Technology Research Group, School of Design, University of Leeds, Leeds LS2 9JT, UK. m.b.bazbouz@leeds.ac.uk.ORCID 0000-0002-0953-6691
Giuseppe TronciTextile Technology Research Group, School of Design, University of Leeds, Leeds LS2 9JT, UK. mbb40@cam.ac.uk.ORCID 0000-0002-9426-4220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spread of antimicrobial resistance calls for chronic wound management devices that can engage with the wound exudate and signal infection by prompt visual effects. Here, the manufacture of a two-layer fibrous device with independently-controlled exudate management capability and visual infection responsivity was investigated by sequential free surface electrospinning of poly(methyl methacrylate-co-methacrylic acid) (PMMA-co-MAA) and poly(acrylic acid) (PAA). By selecting wound pH as infection indicator, PMMA-co-MAA fibres were encapsulated with halochromic bromothymol blue (BTB) to trigger colour changes at infection-induced alkaline pH. Likewise, the exudate management capability was integrated via the synthesis of a thermally-crosslinked network in electrospun PAA layer. PMMA-co-MAA fibres revealed high BTB loading efficiency (>80 wt.%) and demonstrated prompt colour change and selective dye release at infected-like media (pH > 7). The synthesis of the thermally-crosslinked PAA network successfully enabled high water uptake (

Indexed as

AlanineBiological DressingsBromthymol BlueColorDrug Resistance, BacterialHumansHydrogen-Ion ConcentrationNanoparticlesPolymethacrylic AcidsWaterWound HealingWound InfectionWounds and Injuries3-(phenylamino)alanineAlanineBromthymol Bluemethylmethacrylate-methacrylic acid copolymerPolymethacrylic AcidsWaterbromothymol bluecolour changecore-shell fibresfibresfree surface electrospinninginfection

Identifiers

PMID30813559
PMCPMC6427107

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.