Evidence map›Paper›PMID 30813460›Full record

ArticleInternational journal of molecular sciences2019

Metallothionein 3 Is a Hypoxia-Upregulated Oncogene Enhancing Cell Invasion and Tumorigenesis in Human Bladder Carcinoma Cells.

Ke-Hung Tsui, Chen-Pang Hou, Kang-Shuo Chang, Yu-Hsiang Lin, Tsui-Hsia Feng, Chiu-Chun Chen, Yi-Syuan Shin, Horng-Heng Juang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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  7. MetallothioneinMolecules and cells · 2021
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  11. miR-325-3p Overexpression Inhibits Proliferation and Metastasis of Bladder Cancer Cells by Regulating MT3.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ke-Hung TsuiDepartment of Urology, Chang Gung Memorial Hospital-Linkou, Kwei-Shan, Tao-Yuan 33302, Taiwan. t2130@cgmh.org.tw.
Chen-Pang HouDepartment of Urology, Chang Gung Memorial Hospital-Linkou, Kwei-Shan, Tao-Yuan 33302, Taiwan. glucose1979@gmail.com.
Kang-Shuo ChangDepartment of Anatomy, College of Medicine, Chang Gung University, Kwei-Shan, Tao-Yuan 33302, Taiwan. D0501301@stmail.cgu.edu.tw.
Yu-Hsiang LinDepartment of Urology, Chang Gung Memorial Hospital-Linkou, Kwei-Shan, Tao-Yuan 33302, Taiwan. linyh@doctorvoice.org.
Tsui-Hsia FengSchool of Nursing, College of Medicine, Chang Gung University, Kwei-Shan, Tao-Yuan 33302, Taiwan. thf@mail.cgu.edu.tw.
Chiu-Chun ChenDepartment of Medicine, College of Medicine, Chang Gung University, Kwei-Shan, Tao-Yuan 33302, Taiwan. a5880018@gmail.com.
Yi-Syuan ShinDepartment of Medicine, College of Medicine, Chang Gung University, Kwei-Shan, Tao-Yuan 33302, Taiwan. a0956910758@gmail.com.
Horng-Heng JuangDepartment of Urology, Chang Gung Memorial Hospital-Linkou, Kwei-Shan, Tao-Yuan 33302, Taiwan. hhj143@mail.cgu.edu.tw.ORCID 0000-0002-8524-8253
Chang Gung University · TWChang Gung Memorial Hospital · TW

Funding

Chang Gung Memorial Hospital CMRPD1F0141-3Chang Gung Memorial Hospital CMRPG3F081-3Chang Gung Memorial Hospital CMRPG3G0821Chang Gung Memorial Hospital CMRP-G3H1321-3Chang Gung Memorial Hospital CRRPD1F0041-3Taiwan Ministry of Science and Technology MOST-105-2320-B-182-020-MY3Taiwan Ministry of Science and Technology MOST-107-2314-B-182A-017-MY3
6 · The paper itself

Abstract

Metallothioneins have been viewed as modulators in a number of biological regulations regarding cancerous development; however, the function of metallothionein 3 (

Indexed as

OncogenesApoptosisArsenicCarcinogenesisCell HypoxiaCell Line, TumorCell ProliferationDown-RegulationGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansMetallothionein 3Neoplasm InvasivenessNerve Tissue ProteinsN-Myc Proto-Oncogene ProteinTumor Suppressor ProteinsArsenicMetallothionein 3MYCN protein, humanNerve Tissue ProteinsN-Myc Proto-Oncogene ProteinTumor Suppressor ProteinsbladderhypoxiaMASPINmetallothionein 3NDRG1tumorigenesis

Identifiers

PMID30813460
PMCPMC6413184
OpenAlexW2916331088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.