Evidence map›Paper›PMID 30813432›Full record

ArticleCancers2019

Deciphering the Mechanism of Action Involved in Enhanced Suicide Gene Colon Cancer Cell Killer Effect Mediated by Gef and Apoptin.

Blanca Cáceres, Alberto Ramirez, Esmeralda Carrillo, Gema Jimenez, Carmen Griñán-Lisón, Elena López-Ruiz, Yaiza Jiménez-Martínez, Juan A Marchal, Houria Boulaiz

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Silver Nanoparticles fromNanomaterials (Basel, Switzerland) · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. A Winning New Combination? Toward Clinical Application in Oncology.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Blanca CáceresMotril Health Center, Hospital Santa Ana, Motril, 18600 Granada, Spain. blcagr79@gmail.com.
Alberto RamirezBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. alrari80@gmail.com.ORCID 0000-0002-7661-6974
Esmeralda CarrilloBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. esmeral@ugr.es.
Gema JimenezBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. gemajg@ugr.es.
Carmen Griñán-LisónBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. glcarmex@gmail.com.ORCID 0000-0003-3853-6292
Elena López-RuizBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. elruiz@ujaen.es.
Yaiza Jiménez-MartínezBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. yaijmartinez@correo.ugr.es.
Juan A MarchalBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. jmarchal@ugr.es.ORCID 0000-0002-4996-8261
Houria BoulaizBiopathology and Medicine Regenerative Institute (IBIMER), University of Granada, 18016 Granada, Spain. hboulaiz@ugr.es.ORCID 0000-0003-4433-7556
Universidad de Granada · ES

Funding

Consejería de Salud, Junta de Andalucía PI-0089-2017Fundación Mutua Madrileña FMM-AP16683-2017
6 · The paper itself

Abstract

Despite the great advances in cancer treatment, colorectal cancer has emerged as the second highest cause of death from cancer worldwide. For this type of tumor, the use of suicide gene therapy could represent a novel therapy. We recently demonstrated that co-expression of

Indexed as

apoptin geneapoptosiscaspase 3caspase 8caspase 9combined therapygef genenecrosispore

Identifiers

PMID30813432
PMCPMC6406936
OpenAlexW2915944404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.