Evidence map›Paper›PMID 30813423›Full record

ArticleMolecules (Basel, Switzerland)2019

Selective Inhibition of Human Monoamine Oxidase B by Acacetin 7-Methyl Ether Isolated from

Narayan D Chaurasiya, Jianping Zhao, Pankaj Pandey, Robert J Doerksen, Ilias Muhammad, Babu L Tekwani

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Pre-clinical Aspects and Contemporary Treatments of Parkinson's Disease.CNS & neurological disorders drug targets · 2024
    Review
  6. Article
  7. Bioactivity of the GenusPharmaceuticals (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Medicarpin and Homopterocarpin Isolated fromMolecules (Basel, Switzerland) · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Selective Interactions ofMolecules (Basel, Switzerland) · 2020
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Narayan D ChaurasiyaNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. nchaurasiya@southernresearch.org.
Jianping ZhaoNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. jianping@olemiss.edu.
Pankaj PandeyDepartment of BioMolecular Sciences, Division of Medicinal Chemistry and Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. ppandey@olemiss.edu.ORCID 0000-0001-9128-8254
Robert J DoerksenNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. rjd@olemiss.edu.ORCID 0000-0002-3789-1842
Ilias MuhammadNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. milias@olemiss.edu.
Babu L TekwaniNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. btekwani@southernresearch.org.
University of Mississippi · US

Funding

Center of Research Excellence in Natural Products Neuroscience (CORE-NPN)P20GM104932 · NIGMS · UNIVERSITY OF MISSISSIPPI · PI MAJUMDAR, SOUMYAJIT · 2012 to 2016
$10.0M
National Institute of General Medical Sciences (NIGMS) P20GM104932USDA-ARS Specific Cooperative Agreement 58-6408-1-603
6 · The paper itself

Abstract

The investigation of the constituents that were isolated from

Indexed as

Binding SitesFlavonesHumansInhibitory Concentration 50KineticsMethyl EthersMolecular Docking SimulationMolecular Dynamics SimulationMonoamine OxidaseMonoamine Oxidase InhibitorsPlant ExtractsProtein BindingProtein ConformationStructure-Activity RelationshipSubstrate SpecificityTurneraacacetinFlavonesMethyl EthersMonoamine OxidaseMonoamine Oxidase InhibitorsPlant Extractsacacetinacacetin 7-methyl ethermolecular dockingmolecular dynamicsmonoamine oxidase-Amonoamine oxidase-Bneurological disorderTurnera diffusa

Identifiers

PMID30813423
PMCPMC6412401
OpenAlexW2916911856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.