Evidence map›Paper›PMID 30813400›Full record

ArticleInternational journal of molecular sciences2019

Small Molecule Inhibitors Specifically Targeting the Type III Secretion System of

Hui Tao, Su-Su Fan, Shan Jiang, Xuwen Xiang, Xiaojing Yan, Lian-Hui Zhang, Zi-Ning Cui

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Potential and Metabolic Pathways of Eugenol in the Management ofInternational journal of molecular sciences · 2022
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hui TaoState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Integrative Microbiology Research Centre, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China. htao2018@126.com.
Su-Su FanState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China. 1986fansusu@163.com.
Shan JiangState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Integrative Microbiology Research Centre, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China. scaujs@stu.scau.edu.cn.
Xuwen XiangState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Integrative Microbiology Research Centre, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China. xxw@stu.scau.edu.cn.
Xiaojing YanState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China. yanxiaojing@caas.cn.
Lian-Hui ZhangState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Integrative Microbiology Research Centre, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China. lhzhang01@scau.edu.cn.
Zi-Ning CuiState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Integrative Microbiology Research Centre, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China. ziningcui@scau.edu.cn.
State Key Laboratory For Conservation and Utilization of Subtropical Agro-BioresourcesInstitute of Plant Protection · CNSouth China Agricultural University · CN

Funding

the National Key Project for Basic Research (973 Program) 2015CB150600the National Key Research and Development Program of China 2017YFD0200504the National Natural Science Foundation of China 31570122the Opening Foundation of the Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University MSDC 2017-12
6 · The paper itself

Abstract

The initiative strategy for the development of novel anti-microbial agents usually uses the virulence factors of bacteria as a target, without affecting their growth and survival. The type III secretion system (T3SS), one of the essential virulence factors in most Gram-negative pathogenic bacteria because of its highly conserved construct, has been regarded as an effective target that developed new anti-microbial drugs.

Indexed as

Gene Expression Regulation, BacterialGenes, PlantNicotianaOryzaPlant DiseasesPromoter Regions, GeneticSmall Molecule LibrariesType III Secretion SystemsXanthomonasSmall Molecule LibrariesType III Secretion Systemssmall molecule inhibitorsT3SSvirulence factorsXanthomonas oryzae pv. oryzae (Xoo)

Identifiers

PMID30813400
PMCPMC6412923
OpenAlexW2918069829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.