Evidence map›Paper›PMID 30813333›Full record

ReviewInternational journal of molecular sciences2019

Advances in Therapeutic Implications of Inorganic Drug Delivery Nano-Platforms for Cancer.

Safia Naz, Muhammad Shamoon, Rui Wang, Li Zhang, Juan Zhou, Jinghua Chen

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Implications of the molecular toxicity and cytocompatibility by the nano-caged CNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. HCDT: an integrated highly confident drug-target resource.Database : the journal of biological databases and curation · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Diflunisal Targeted Delivery Systems: A Review.Materials (Basel, Switzerland) · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Safia NazKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China. safianaz26@hotmail.com.ORCID 0000-0003-1641-8244
Muhammad ShamoonMedical School, The Australian National University, Canberra ACT 2600, Australia. shamoon1096@gmail.com.ORCID 0000-0003-0496-3544
Rui WangKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China. jiangnanwangrui@163.com.
Li ZhangKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China. 6181504017@stu.jiangnan.edu.cn.
Juan ZhouKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China. juanzhou@jiangnan.edu.cn.ORCID 0000-0001-9770-7229
Jinghua ChenKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, China. chenjinghua@jiangnan.edu.cn.
Jiangnan University · CNAustralian National University · AU

Funding

National First-class Discipline Program of Light Industry Technology and Engineering LITE2018-20National Natural Science Foundation of China 21574059National Natural Science Foundation of Jiangsu Province BK20170203
6 · The paper itself

Abstract

Numerous nanoparticles drug delivery systems for therapeutic implications in cancer treatment are in preclinical development as conventional chemotherapy has several drawbacks. A chemotherapeutic approach requires high doses of chemotherapeutic agents with low bioavailability, non-specific targeting, and above all, development of multiple drug resistance. In recent years, inorganic nano-drug delivery platforms (NDDPs; with a metal core) have emerged as potential chemotherapeutic systems in oncology. One of the major goals of developing inorganic NDDPs is to effectively address the targeted anti-cancer drug(s) delivery related problems by carrying the therapeutic agents to desired tumors sites. In this current review, we delve into summarizing the recent developments in targeted release of anti-cancer drugs loaded in inorganic NDDPs such as mesoporous silica nanoparticles, carbon nanotubes, layered double hydroxides, superparamagnetic iron oxide nanoparticles and calcium phosphate nanoparticles together with highlighting their therapeutic performance at tumor sites.

Indexed as

Drug Delivery SystemsAnimalsCalcium PhosphatesDrug CarriersHumansInorganic ChemicalsNanoparticlesNeoplasmscalcium phosphateCalcium PhosphatesDrug CarriersInorganic Chemicalscancerdrug deliveryinorganic agentsnano-carrierstherapeutics

Identifiers

PMID30813333
PMCPMC6413464
OpenAlexW2918028002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.