ArticleCancers2019
The Role of Lactate Metabolism in Prostate Cancer Progression and Metastases Revealed by Dual-Agent Hyperpolarized
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Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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0cells of the map it votes in
36citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 64 citations in OpenAlex.
- Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review).Oncology reports · 2026Review
- MR-based techniques for imaging prostate cancer metabolism: current status and future perspectives.Abdominal radiology (New York) · 2026Review
- Review
- Bone Metastatic Progression of Prostate Cancer Is Regulated by TRIM28-LDHA-Mediated Metabolism.Molecular cancer research : MCR · 2026Article
- Multivariate Framework of Metabolism in Advanced Prostate Cancer Using Whole Abdominal and Pelvic HyperpolarizedCancers · 2025Article
- Metabolic and imaging phenotypes associated withbioRxiv : the preprint server for biology · 2025Article
- Review
- Immune microenvironment regulation and clinical immunotherapy strategies of metastatic liver cancer.Frontiers in immunology · 2025Review
- Translation of hyperpolarized [Npj imaging · 2025Article
- A Scaled Proteomic Discovery Study for Prostate Cancer Diagnostic Markers Using ProteographInternational journal of molecular sciences · 2024Article
- Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer.Cancer research · 2024Article
- Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023Article
- Metabolomic profiles of intact tissues reflect clinically relevant prostate cancer subtypes.Journal of translational medicine · 2023Article
- Lactate as Key Metabolite in Prostate Cancer Progression: What Are the Clinical Implications?Cancers · 2023Review
- Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis.bioRxiv : the preprint server for biology · 2023Article
- Differences in the pathogenetic characteristics of prostate cancer in the transitional and peripheral zones and the possible molecular biological mechanisms.Frontiers in oncology · 2023Review
- Innate lymphoid cells and tumor-derived lactic acid: novel contenders in an enduring game.Frontiers in immunology · 2023Review
- Evolutionary View on Lactate-Dependent Mechanisms of Maintaining Cancer Cell Stemness and Reprimitivization.Cancers · 2022Review
- Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [Magnetic resonance in medicine · 2022Article
- SU086, an inhibitor of HSP90, impairs glycolysis and represents a treatment strategy for advanced prostate cancer.Cell reports. Medicine · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Robert BokDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. Robert.Bok@ucsf.edu.
Jessie LeeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. Jessie.Lee@ucsf.edu.
Renuka SriramDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. Renuka.Sriram@ucsf.edu.ORCID 0000-0003-3505-2479
Kayvan KeshariDepartment of Radiology, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY 10065, USA. rahimikk@mskcc.org.
Subramaniam SukumarDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. ssukumar@live.com.
Saeed DaneshmandiDepartment of Medicine, Division of Interdisciplinary Medicine, Beth Israel Deaconess Medical Center, Beth Israel Cancer Center, Harvard Medical School, Boston, MA 02215, USA. sdaneshm@bidmc.harvard.edu.
David E KorenchanDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. Dave.Korenchan@ucsf.edu.
Robert R FlavellDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. Robert.Flavell@ucsf.edu.
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. Dan.Vigneron@ucsf.edu.
John KurhanewiczDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. john.kurhanewicz@ucsf.edu.ORCID 0000-0002-3544-5339
Pankaj SethDepartment of Medicine, Division of Interdisciplinary Medicine, Beth Israel Deaconess Medical Center, Beth Israel Cancer Center, Harvard Medical School, Boston, MA 02215, USA. pseth@bidmc.harvard.edu.
University of California, San Francisco · USBeth Israel Deaconess Medical Center · USMemorial Sloan Kettering Cancer Center · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MApplication of hyperpolarized 13C interstitial pH imaging to risk stratification in prostate cancerR21EB026012 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FLAVELL, ROBERT RICHARD · 2018 to 2020
$503kNCI NIH HHS P30 CA008748NIBIB NIH HHS R21 EB026012
Abstract
This study applied a dual-agent,
Indexed as
hyperpolarized 13Clactatelactate dehydrogenasemagnetic resonance imagingprostate cancer
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.