Evidence map›Paper›PMID 30813265›Full record

ReviewMicroorganisms2019

Can Gut Microbiota and Lifestyle Help Us in the Handling of Anorexia Nervosa Patients?

Vanessa Mendez-Figueroa, Jose Miguel Biscaia, Rosa B Mohedano, Ascension Blanco-Fernandez, Maria Bailen, Carlo Bressa, Mar Larrosa, Rocio Gonzalez-Soltero

Abstract readReview
In one paragraph

Review in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vanessa Mendez-FigueroaFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. vanessamendez@hotmail.com.
Jose Miguel BiscaiaFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. josemiguel.biscaia@universidadeuropea.es.
Rosa B MohedanoFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. rosabelen.mohedano@universidadeuropea.es.
Ascension Blanco-FernandezFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. ascension.blanco@universidadeuropea.es.
Maria BailenFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. maria.bailen@universidadeuropea.es.ORCID 0000-0001-5201-906X
Carlo BressaFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. carlo.bressa@universidadeuropea.es.ORCID 0000-0001-5530-4958
Mar LarrosaFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. mar.larrosa@universidadeuropea.es.ORCID 0000-0002-8863-4686
Rocio Gonzalez-SolteroFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain. mariadelrocio.gonzalez@universidadeuropea.es.

Funding

Cátedra ASISA-Universidad Europea 2015/UEM46Ministerio de Economía, Industria y Competitividad, Gobierno de España AGL2016-77288-RRamón y Cajal grant 2012_11910
6 · The paper itself

Abstract

Gut microbiota is composed of different microorganisms that play an important role in the host. New research shows that bidirectional communications happen between intestinal microbiota and the brain, which is known as the gut⁻brain axis. This communication is significant and could have a negative or positive effect depending on the state of the gut microbiota. Anorexia nervosa (AN) is a mental illness associated with metabolic, immunologic, biochemical, sensory abnormalities, and extremely low body weight. Different studies have shown a dysbiosis in patients with AN. Due to the gut⁻brain axis, it was observed that some of the symptoms could be improved in these patients by boosting their gut microbiota. This paper highlights some evidence connecting the role of microbiota in the AN onset and disease progress. Finally, a proposal is done to include the microbiota analysis as part of the recovery protocol used to treat AN patients. When conducting clinical studies of gut microbiota in AN patients, dysbiosis is expected to be found. Then the prescription of a personalized treatment rich in prebiotics and probiotics could be proposed to reverse the dysbiosis.

Indexed as

anorexia nervosadysbiosiseating disordersgut–brain-axisgut microbiota

Identifiers

PMID30813265
PMCPMC6406897

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.