Evidence map›Paper›PMID 30813241›Full record

ArticleMolecules (Basel, Switzerland)2019

Increased Selectivity of Novozym 435 in the Asymmetric Hydrolysis of a Substrate with High Hydrophobicity Through the Use of Deep Eutectic Solvents and High Substrate Concentrations.

Yerko Fredes, Lesly Chamorro, Zaida Cabrera

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yerko FredesSchool of Biochemical Engineering, Pontificia Universidad Católica de Valparaíso; Avda. Brasil 2085 Valparaíso, Chile. y.a.fredes@gmail.com.
Lesly ChamorroSchool of Biochemical Engineering, Pontificia Universidad Católica de Valparaíso; Avda. Brasil 2085 Valparaíso, Chile. leslychamorromolina@gmail.com.
Zaida CabreraSchool of Biochemical Engineering, Pontificia Universidad Católica de Valparaíso; Avda. Brasil 2085 Valparaíso, Chile. zaida.cabrera@pucv.cl.
Pontificia Universidad Católica de Valparaíso · CL

Funding

Towards eliminating HIV in Uganda by 2030; Preparing Ethical Review Committees to support this agendaG11TW011309 · FIC · INFECTIOUS DISEASES INSTITUTE · PI BYAKIKA-KIBWIKA, PAULINE · 2019 to 2021
$373k
Comisión Nacional de Investigación Científica y Tecnológica Fondecyt 1130981Pontificia Universidad Católica de Valparaiso DI asignable 203.799/2013
6 · The paper itself

Abstract

The effects of the reaction medium and substrate concentration were studied on the selectivity of Novozym 435 using the asymmetric hydrolysis of dimethyl-3-phenylglutarate as a model reaction. Results show that the use of choline chloride ChCl:urea/phosphate buffer 50% (

Indexed as

CholineEnzymes, ImmobilizedFungal ProteinsGlutaratesHydrogen-Ion ConcentrationHydrolysisHydrophobic and Hydrophilic InteractionsLipaseSolventsStereoisomerismSubstrate SpecificityTemperatureCholineEnzymes, ImmobilizedFungal ProteinsGlutaratesLipaseNovozyme 435Solventsasymmetric synthesisdeep eutectic solventsdimethyl-3-phenylglutaratehydrophobic substratesNovozym 435

Identifiers

PMID30813241
PMCPMC6412981
OpenAlexW2916003421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.