ReviewMaterials science & engineering. C, Materials for biological applications2019
Zirconia surface modifications for implant dentistry.
Review in Materials science & engineering. C, Materials for biological applications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
99 citing papers in PubMed, 292 citations in OpenAlex.
- When bioactivity comes at a mechanical cost: toward mechanically safe bioactivation of zirconia dental implants.Bioactive materials · 2027Review
- Cellular Responses at the Zirconia Dental Implant Interface: A Comprehensive Review.Journal of functional biomaterials · 2026Review
- Advancements in Individual Dental Implants: A State-of-the-Art Review of Materials and Technologies.Materials (Basel, Switzerland) · 2026Review
- Meso-Scale Modifications in Additively Manufactured Zirconia: Topographical Design and Its Influence on Cell-Material Interactions.Bioengineering (Basel, Switzerland) · 2026Article
- Mussel-inspired silica, strontium, and fluoride-doped hydroxyapatite/BMP-2 composite coating: a new strategy to enhance the bioactivity of zirconia implants.RSC advances · 2026Article
- The dental implant surface: a review of the past, present and future.Journal of materials science. Materials in medicine · 2026Review
- Selective Infiltration Etching as a surface modification for high-translucency zirconia: Comparative analysis of roughness, composition, and bond strength.F1000Research · 2026Article
- In Vitro and In Vivo Evaluation of Yttria-Niobia-Stabilized Zirconia Sandblasted Surface at Bone-Implant Interface with 3-Dimensional Visualization via Advanced Hard Tissue Clearing.Biomaterials research · 2026Article
- Simulated oral environment affects zirconia aging and mechanical strength.Journal of the mechanical behavior of biomedical materials · 2026Article
- Clinical trial of dental implants in titanium-zirconium alloy compared to titanium.Bioinformation · 2026Article
- Effects of Laser Applications on Fibroblasts Cultured on Zirconia Surfaces-A Systematic Review.Journal of clinical medicine · 2025Review
- Long term follow-up of immediately temporized zirconia and titanium one-piece dental implants-a prospective cohort study.International journal of implant dentistry · 2025Article
- Impact of Laser Surface Modification on Zirconia Implants: A Systematic Review of In Vitro Evidence.Cureus · 2025Review
- Comparative Animal Study of Zirconia-Coated Titanium Implants: Effect on Bone Formation and Collagen Fiber Orientation.Journal of functional biomaterials · 2025Article
- Hybrid TiONature communications · 2025Article
- Handheld Nonthermal Plasma Augmentation of Glass-Ceramic Spray Deposition on Zirconia Surface Characterization and MG-63/HGF-1 Cell Behavior: An In Vitro Study.Journal of functional biomaterials · 2025Article
- Monitoring and Evaluation of Corrosion at the Interface of Zirconium Alloy Biomaterials Under Simulated Oxidative Biological Environment.International journal of molecular sciences · 2025Article
- Osseointegration properties of niobia-modified yttria-stabilized zirconia implant surface: anThe journal of advanced prosthodontics · 2025Article
- Enhancing Osseointegration of Zirconia Implants Using Calcium Phosphate Coatings: A Systematic Review.Materials (Basel, Switzerland) · 2025Review
- Promoting Surface Energy and Osteoblast Viability on Zirconia Implant Abutments Through Glass-Ceramic Spray Deposition Technology.Journal of functional biomaterials · 2025Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundZirconia has emerged as a versatile dental material due to its excellent aesthetic outcomes such as color and opacity, unique mechanical properties that can mimic the appearance of natural teeth and decrease peri-implant inflammatory reactions.
objectiveThe aim of this review was to critically explore the state of art of zirconia surface treatment to enhance the biological and osseointegration behavior of zirconia in implant dentistry. MATERIALS AND
methodsAn electronic search in PubMed database was carried out until May 2018 using the following combination of key words and MeSH terms without time periods: "zirconia surface treatment" or "zirconia surface modification" or "zirconia coating" and "osseointegration" or "biological properties" or "bioactivity" or "functionally graded properties".
resultsPrevious studies have reported the influence of zirconia-based implant surface on the adhesion, proliferation, and differentiation of osteoblast and fibroblasts at the implant to bone interface during the osseointegration process. A large number of physicochemical methods have been used to change the implant surfaces and therefore to improve the early and late bone-to-implant integration, namely: acid etching, gritblasting, laser treatment, UV light, CVD, and PVD. The development of coatings composed of silica, magnesium, graphene, dopamine, and bioactive molecules has been assessed although the development of a functionally graded material for implants has shown encouraging mechanical and biological behavior.
conclusionModified zirconia surfaces clearly demonstrate faster osseointegration than that on untreated surfaces. However, there is no consensus regarding the surface treatment and consequent morphological aspects of the surfaces to enhance osseointegration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.