ArticleInvestigative ophthalmology & visual science2019
Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study.
Article in Investigative ophthalmology & visual science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Structure-function relationships of circumpapillary choroidal thickness in normal-tension glaucoma with and without high myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- The prevalence of epiretinal membrane in pseudoexfoliation and primary open-angle glaucoma and its association with choroidal thickness.International ophthalmology · 2025Observational
- Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements.Investigative ophthalmology & visual science · 2024Article
- Long-Term Changes in Lamina Cribrosa Curvature Index After Trabeculectomy in Glaucomatous Eyes.Investigative ophthalmology & visual science · 2024Observational
- Choroidal and Retinal Thicknesses in Healthy Eyes Measured with Ultra-Wide-Field Optical Coherence Tomography.Diagnostics (Basel, Switzerland) · 2024Article
- OCT Optic Nerve Head Morphology in Myopia IV: Neural Canal Scleral Flange Remodeling in Highly Myopic Eyes.American journal of ophthalmology · 2024Article
- Heterogenous thinning of peripapillary tissues occurs early during high myopia development in juvenile tree shrews.Experimental eye research · 2024Article
- Optical Coherence Tomographic Optic Nerve Head Morphology in Myopia III: The Exposed Neural Canal Region in Healthy Eyes-Implications for High Myopia.American journal of ophthalmology · 2024Article
- Deep Optic Nerve Head Morphology in Tilted Disc Syndrome and Its Clinical Implication on Visual Damage.Investigative ophthalmology & visual science · 2023Article
- Differences in Central and Peripheral Choroidal Thickness among the Subtypes of Age-Related Macular Degeneration in an Asian Population.Journal of clinical medicine · 2023Article
- OCT Optic Nerve Head Morphology in Myopia II: Peri-Neural Canal Scleral Bowing and Choroidal Thickness in High Myopia-An American Ophthalmological Society Thesis.American journal of ophthalmology · 2023Article
- Deep Optic Nerve Head Structures Associated With Increasing Axial Length in Healthy Myopic Eyes of Moderate Axial Length.American journal of ophthalmology · 2023Observational
- The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects.Korean journal of ophthalmology : KJO · 2022Article
- Comparison of lamina cribrosa depth shallowing after trabeculectomy between primary open-angle glaucoma and exfoliation glaucoma.Scientific reports · 2022Article
- Offset of openings in optic nerve head canal at level of Bruch's membrane, anterior sclera, and lamina cribrosa.Scientific reports · 2021Article
- Peripapillary choroidal thickness assessed by spectral-domain optical coherence tomography in normal Japanese.Japanese journal of ophthalmology · 2021Article
- The influence of axial myopia on optic disc characteristics of glaucoma eyes.Scientific reports · 2021Article
- Histologic validation of optical coherence tomography-based three-dimensional morphometric measurements of the human optic nerve head: Methodology and preliminary results.Experimental eye research · 2021Article
- Optical Coherence Tomography Optic Nerve Head Morphology in Myopia I: Implications of Anterior Scleral Canal Opening Versus Bruch Membrane Opening Offset.American journal of ophthalmology · 2020Article
- Peripapillary Scleral Bowing Increases with Age and Is Inversely Associated with Peripapillary Choroidal Thickness in Healthy Eyes.American journal of ophthalmology · 2020Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Purpose: To quantify peripapillary choroidal thickness (PCT) and the factors that influence it in healthy participants who represent the racial and ethnic composition of the U.S. population. Methods: A total of 362 healthy participants underwent optical coherence tomography (OCT) enhanced depth imaging of the optic nerve head with a 24 radial B-scan pattern aligned to the fovea to Bruch's membrane opening axis. Bruch's membrane, anterior scleral canal opening (ASCO), and the anterior scleral surface were manually segmented. PCT was measured at 100, 300, 500, 700, 900, and 1100 μm from the ASCO globally and within 12 clock-hour sectors. The effects of age, axial length, intraocular pressure, ethnicity, sex, sector, and ASCO area on PCT were assessed by ANOVA and univariable and multivariable regressions. Results: Globally, PCT was thicker further from the ASCO border and thinner with older age, longer axial length, larger ASCO area, European descent, and female sex. Among these effectors, age and axial length explained the greatest proportion of variance. The rate of age-related decline increased further from the ASCO border. Sectorally, the inferior-temporal sectors were thinnest (10.7%-20.0% thinner than the thickest sector) and demonstrated a higher rate of age-related loss (from 15.6% to 20.7% faster) at each ASCO distance. Conclusions: In healthy eyes, PCT was thinnest in the inferior temporal sectors and thinner PCT was associated with older age, European descent, longer axial length, larger ASCO area, and female sex. Among these associations, age had the strongest influence, and its effect was greatest within the inferior temporal sectors.
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