ReviewPLoS medicine2019
Constructing care cascades for active tuberculosis: A strategy for program monitoring and identifying gaps in quality of care.
Review in PLoS medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
134 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Implementation strategies to increase the uptake and impact of molecular WHO-recommended rapid diagnostic tests: evidence from a mixed-methods systematic review.BMJ global health · 2025Pooled it
- Barriers to engagement in the care cascade for tuberculosis disease in India: A systematic review of quantitative studies.PLoS medicine · 2024Pooled it
- Improving cascade outcomes for active TB: A global systematic review and meta-analysis of TB interventions.PLoS medicine · 2023Pooled it
- Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis.The Cochrane database of systematic reviews · 2021Pooled it
- Pooled it
- Providing person-centred TB care: a participatory study with healthcare workers in Nairobi, Kenya.BMJ open · 2026Article
- "Fragmented care pathway in a layered TB care system": a grounded theory approach to understand care pathways and delays in TB care in Odisha.BMC health services research · 2026Article
- Article
- Artificial Intelligence for Tuberculosis Screening and Detection: From Evidence to Policy and Implementation.Diagnostics (Basel, Switzerland) · 2026Review
- Implementation of digital tuberculosis information systems: perspectives from 10 high TB burden countries.BMC infectious diseases · 2026Article
- Stakeholder engagement to identify barriers to implementation and inform the development of point-of-care diagnostics for TB.IJTLD open · 2026Article
- Delays in tuberculosis care among the top-ten-tuberculosis-high burden countries in the world: a scoping review.The Journal of the Egyptian Public Health Association · 2026Review
- Delays in tuberculosis diagnosis and treatment in India: A patient journey analysis from Mumbai and Patna during the COVID-19 Pandemic.PLOS global public health · 2026Article
- Reaching the 100 by 2027 target for universal access to rapid molecular diagnostic tests for tuberculosis in Africa: In-sight but out of reach.PLOS global public health · 2026Article
- Assessing tuberculosis stigma: a pooled multi-country descriptive analysis of 17 high-burden countries using a standardised tool.Frontiers in public health · 2026Article
- Pursuing policymakers, payors and public - expanding the beginning and end of the tuberculosis care cascade to reflect whole-of-society ambitions.PLOS global public health · 2026Article
- Determinants of drop-offs in the targeted universal tuberculosis testing care cascade among people with HIV in rural and urban facilities in South Africa.Southern African journal of HIV medicine · 2026Article
- Improving Tuberculosis Treatment Outcomes in Somalia: A Narrative Review of Strategies, Challenges, and Policy Recommendations.Risk management and healthcare policy · 2026Review
- Strengthening comprehensive tuberculosis care in Angola: a scoping review of strategies, challenges, and potentialities in a high-burden setting.Public health reviews · 2026Review
- Tuberculosis Diagnostic Delays in Indonesian Primary Care Pathways.Annals of global health · 2026Observational
74 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The cascade of care is a model for evaluating patient retention across sequential stages of care required to achieve a successful treatment outcome. This approach was first used to evaluate HIV care and has since been applied to other diseases. The tuberculosis (TB) community has only recently started using care cascade analyses to quantify gaps in quality of care. In this article, we describe methods for estimating gaps (patient losses) and steps (patients retained) in the care cascade for active TB disease. We highlight approaches for overcoming challenges in constructing the TB care cascade, which include difficulties in estimating the population-level burden of disease and the diagnostic gap due to the limited sensitivity of TB diagnostic tests. We also describe potential uses of this model for evaluating the impact of interventions to improve case finding, diagnosis, linkage to care, retention in care, and post-treatment monitoring of TB patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.